PMID: 9527942Apr 7, 1998Paper

Factors affecting humidity of inspired gas in a neonatal lung model

Journal of Perinatology : Official Journal of the California Perinatal Association
A RiosA R Fleischman

Abstract

The American National Standards Institute recommends an absolute humidity of > or = 30 mg/L of inspired gas in patients receiving mechanical ventilation. This study was designed to assess the absolute humidity of inspired gas in relation to humidifier settings and environmental conditions in a test lung. Measurements were obtained at the endotracheal tube manifold of an artificial lung in an isolette or radiant warmer with use of a nonheated wired system and two different ventilator circuit lengths. Temperature and relative humidity were measured at three environmental temperatures and various humidifier settings. We achieved adequate absolute humidity levels only at near maximum humidifier settings. When the artificial lung was placed in an isolette with a standard circuit length inside the isolette, adequate absolute humidity was never reached at an environmental temperature of 30 degrees C. Increasing the length of the ventilator circuit situated inside the isolette or using a radiant warmer improved absolute humidity compared with that obtained with use of a standard circuit length. Recommended absolute humidity levels may not be reached at the manifold even at high humidifier settings. Thus actual measurements of relative ...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.