PMID: 6112664Jan 20, 1981Paper

Factors affecting induction of tyrosine aminotransferase in isolated rat liver cells

Molecular and Cellular Biochemistry
F A MarstonC I Pogson

Abstract

1. The response of tyrosine aminotransferase activity in isolated liver cells has been studied under several conditions. 2. Activity is increased over a 5 h period by both glucagon and glucocorticoids in cells from adrenalectomized rats. The results do not support the view that glucagon action is dependent on preexposure of cells to steroid. 3. In cells from fed animals, significant stimulation is seen only when both glucagon and steroid are present together. 4. In cells from 48 h fasted rats steroid is effective, but glucagon is not significant so. 5. These anomalies are attributed to the differences in hormonal and nutritional status between the animals from which the cells are isolated.

References

Sep 20, 1976·Biochemical and Biophysical Research Communications·J M NickolF T Kenney
Jan 1, 1977·The Journal of Cell Biology·L J Crane, D L Miller
Nov 15, 1977·FEBS Letters·F A Marston, C I Pogson
Jan 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·M D Roper, W D Wicks
Jan 1, 1976·Methods in Cell Biology·P O Seglen
May 15, 1979·Biochemical Pharmacology·S A SmithC I Pogson
Dec 15, 1978·The Biochemical Journal·S A SmithC I Pogson
Nov 1, 1977·FEBS Letters·A J Dickson, C I Pogson
Aug 1, 1974·Archives of Biochemistry and Biophysics·D J McNamara, T E Webb
Jan 1, 1971·The Biochemical Journal·R A Stinson, H Gutfreund
Jul 28, 1968·Journal of Molecular Biology·D K GrannerG M Tomkins
Oct 1, 1957·Biochimica Et Biophysica Acta·E C LIN, W E KNOX

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