Abstract
The aim of this study is to clarify the factors affecting physical function after allogeneic hematopoietic stem cell transplantation (HSCT). We retrospectively analyzed 88 patients (median age, 44.5 years) who received allogeneic HSCT. Leg extension torque and peak oxygen consumption (VO2) were evaluated before and after HSCT. Patient factors (age, sex, underlying diseases, hemoglobin, serum albumin, and Karnofsky performance status score before transplant) and transplant factors (conditioning regimen, days to neutrophil engraftment, grades of acute graft-versus-host disease [GVHD], infections, and the interval between pre- and post-evaluation) were collected via chart review, and were used for correlational and comparison analyses in order to identify the variables associated with reduced post-HSCT leg extension torque and peak VO2. Stepwise multiple regression analyses for post-HSCT leg extension torque and post-HSCT peak VO2 were performed using age, sex, and the related variables with a p value < 0.2 in the correlational and comparison analyses. Leg extension torque and peak VO2 were significantly reduced after HSCT (p < 0.001). Pre-HSCT leg extension torque, grades of acute GVHD, age, and the interval between pre- and post...Continue Reading
References
Nov 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·B A CunninghamP Lenssen
Sep 1, 1984·Anesthesiology·Y ShimadaN Taenaka
Nov 1, 1994·Circulation·A KoikeF Marumo
Jan 23, 1999·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·N GledhillV Jamnik
Oct 23, 2001·Sports Medicine·D J Macfarlane
Jul 13, 2002·Muscle & Nerve·Andrea MacalusoGiuseppe De Vito
May 17, 2003·Leukemia·A GratwohlUNKNOWN Lymphoma Working Party
Sep 18, 2003·Bone Marrow Transplantation·M MelloF L Dulley
Oct 27, 2004·Journal of the American Society of Nephrology : JASN·Michelle C OddenMichael G Shlipak
Mar 22, 2005·European Journal of Haematology·Martin KoppDavid Nachbaur
Jan 6, 2007·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Joacim LarsenAnn Gardulf
Jul 21, 2007·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Todd E DeForDaniel J Weisdorf
Nov 15, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Keitaro KuboTetsuo Fukunaga
Feb 24, 2009·Bone Marrow Transplantation·M JardenL Adamsen
Jul 15, 2009·Bone Marrow Transplantation·F T BaumannA A Fauser
Apr 17, 2010·Journal of Sports Sciences·Massimiliano DitroiloGiuseppe De Vito
Sep 25, 2010·Journal of Applied Physiology·Lars HvidCharlotte Suetta
Dec 1, 2010·Cancer Nursing·Eileen Danaher HackerLisa Gaston
Dec 31, 2010·Blood·Joachim WiskemannMartin Bohus
Apr 12, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Shinichiro MorishitaKazuhisa Domen
May 7, 2011·European Journal of Haematology·Freerk T BaumannWilhelm Bloch
Apr 19, 2012·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Paul J MartinPaul A Carpenter
Aug 28, 2012·Bone Marrow Transplantation·P UrbainH-K Biesalski
Dec 12, 2012·Physical Therapy·Inge E P M van HarenMaria W G Nijhuis-van der Sanden
Mar 12, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Shinichiro MorishitaKazuhisa Domen
Mar 15, 2013·Cancer Treatment Reviews·Saskia PersoonMai J M Chinapaw
Apr 16, 2013·Bone Marrow Transplantation·W A WoodC Battaglini
Sep 27, 2014·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Takahiro TakekiyoAtae Utsunomiya
Nov 12, 2014·The Cochrane Database of Systematic Reviews·Nils BergenthalNicole Skoetz
May 9, 2015·BMC Pulmonary Medicine·Marcello FerrariRenato Testi
May 15, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Amir SteinbergJack B Fu
May 27, 2015·PloS One·Daniela BenedettoSusanna Sciomer
Oct 9, 2015·The Oncologist·Lee W JonesAnn A Jakubowski
Oct 4, 2016·European Journal of Internal Medicine·Gaia CattadoriUNKNOWN MECKI score Research Group (appendix)
Nov 1, 2016·[Rinshō ketsueki] The Japanese journal of clinical hematology·Makoto Murata
Jan 18, 2018·Physiotherapy Theory and Practice·Inge E P M van HarenMaria W G Nijhuis-van der Sanden
Citations
May 28, 2019·The Journal of the International Society of Physical and Rehabilitation Medicine·Shinichiro MorishitaShigeo Fuji
Nov 13, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Ryota HamadaShuichi Matsuda
Jun 18, 2020·Journal of Clinical Medicine·Daniel Santa MinaEugene Chang
Jan 7, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Vesile Yildiz KabakTulin Duger
Apr 1, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Tatsushi WakasugiKazuhisa Domen