Factors affecting short-term neurodevelopmental outcome in children operated on for major congenital anomalies

Journal of Pediatric Surgery
Francesca BevilacquaLucia Aite

Abstract

Identify clinical and socio-demographic risk-factors affecting short-term neurodevelopmental outcome (NDO) in children operated on for abdominal and thoracic congenital anomalies (CA). Prospective cohort observational study on newborns operated on for non-cardiac major CA. Evaluations were conducted at 6 and 12 months of age. Univariate linear regression and multivariate regression were conducted to analyze the impact on NDO of clinical and sociodemographic variables. Infants were evaluated with the Bayley Scales of Infant and Toddler Development-3rd Edition. One-hundred-fifty-five children were enrolled. They were affected by the following anomalies: Esophageal Atresia (N=41), Congenital Diaphragmatic Hernia (N=42), Midgut Malformations (N=34), Abdominal Wall Defects (N=18), Colorectal Malformations (N=20). There were no statistically significant differences among the five groups of CA as to NDO. Variables which reached statistical significance at multivariate regression (p≤0.001) at 6 and 12 months as to cognitive and motor development were: ventilatory time, associated malformations, medical appliances for feeding, number of surgery and length of hospital stay. On the average, children born with CA show a NDO within normal r...Continue Reading

References

Aug 24, 2004·Child: Care, Health and Development·S D PedersenD Dewey
May 4, 2005·Journal of Pediatric Surgery·Raul A CortesKerilyn K Nobuhara
Jul 4, 2009·Journal of Pediatric Surgery·Saskia J GischlerDick Tibboel
Aug 4, 2010·Early Human Development·Monique H M van der Cammen-van ZijpHanneke Ijsselstijn
Nov 26, 2010·Journal of Paediatrics and Child Health·Sharon LaingKaye Spence
Dec 24, 2010·Developmental Medicine and Child Neurology·Petra MazerHugo J Duivenvoorden
Jun 7, 2011·Early Human Development·Enrico Danzer, Holly L Hedrick
Aug 2, 2012·Circulation·Bradley S MarinoUNKNOWN American Heart Association Congenital Heart Defects Committee, Council on Cardiovascular Disease in the Young, Council on Ca
May 11, 2013·Journal of Perinatology : Official Journal of the California Perinatal Association·E DanzerH L Hedrick
Mar 10, 2015·Journal of Pediatric Surgery·Francesca BevilacquaLucia Aite

❮ Previous
Next ❯

Citations

Jun 2, 2017·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Patricia FleckSandra Mott
Jun 16, 2017·Archives of Disease in Childhood. Fetal and Neonatal Edition·Annelieke HijkoopTitia E Cohen-Overbeek
Mar 23, 2018·Archives of Disease in Childhood. Fetal and Neonatal Edition·Annelieke HijkoopHanneke IJsselstijn
Apr 8, 2020·World Journal of Gastroenterology : WJG·Isabelle TrainiUsha Krishnan
Nov 4, 2020·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Bevilacqua FrancescaAite Lucia
Jun 12, 2021·Archives of Disease in Childhood. Fetal and Neonatal Edition·Daniëlle RoordaJaap Oosterlaan
Aug 12, 2021·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Camille E van HoornJurgen C de Graaff

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.