PMID: 6110748Dec 1, 1980Paper

Factors affecting the release and excretion of dopamine in the rat

The Journal of Pharmacy and Pharmacology
M J AkpaffiongB Woodward

Abstract

The effects of inorganic salts and of diuretic agents on the excretion of dopamine (DA) were examined in the rat. Both types of treatment evoked significant increases in urinary DA excretion, urine volume and urinary sodium excretion. In the salt-treated animals a significant correlation was observed between DA excretion and urine volume, whereas after diuretic treatment there was better correlation between DA and urinary sodium excretion. The salt-treated animals showed a high correlation between administered chloride and DA excretion. Subcutaneous administration of DA produced a significant diuresis and an increase in sodium excretion. The mechanisms responsible for these responses are discussed with reference to the possibility that DA has a physiological role in the kidney.

References

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Citations

Dec 15, 1990·European Journal of Pharmacology·R Dawson, M I Phillips
Dec 5, 1998·Pharmacology & Therapeutics·P A JoseR A Felder
Feb 26, 2000·Acta Physiologica Scandinavica·R A FelderP A Jose
Sep 1, 1983·Clinical and Experimental Pharmacology & Physiology·B P McGrathG C Smith
Jan 1, 1987·Clinical and Experimental Hypertension. Part A, Theory and Practice·C Bell
Jan 1, 1993·Clinical and Experimental Hypertension : CHE·C T StierY H Chen
Jan 1, 1987·Clinical and Experimental Hypertension. Part A, Theory and Practice·M L DeFeoM F Lokhandwala
May 1, 1983·British Journal of Pharmacology·M J AkpaffiongB Woodward
Feb 1, 1986·Arzneimittel-Forschung
Sep 1, 1982·Journal of Autonomic Pharmacology·M F Lokhandwala, R J Barrett
Sep 24, 2013·Journal of Neurosurgery·Olivier HeckSerge Bracard
Feb 4, 2003·Experimental Biology and Medicine·Tahir Hussain, Mustafa F Lokhandwala
May 1, 1991·The American Journal of Physiology·M HayashiT Saruta

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