Factors affecting tissue aluminum concentration

Journal of Dialysis
G H MayorJ B Hook

Abstract

Elevated concentration of aluminum has been reported in serum, whole blood and tissue samples of patients with renal insufficiency. Evidence incriminating aluminum as a neurotoxin among the dialysis population is strong. The source of this aluminum has not been clearly defined, although both gastrointestinal and parenteral routes may be involved. Data from this laboratory suggest that an effect of parathyroid hormone on tissue aluminum burdens may, in part, explain why only certain patients exposed to high dialysate aluminum develop the dialysis encephalopathy syndrome and the occasional occurrence of this syndrome in the absence of dialysis or increased dialysate aluminum.

References

Jun 5, 1976·Lancet·J A FlendrigH A Das
Apr 29, 1978·Lancet·J R McDermottD N Kerr
Jun 3, 1978·Lancet·H L ElliottG S Fell
Nov 1, 1977·Kidney International·W D KaehnyW J Shorr
Apr 1, 1978·Annals of Internal Medicine·G DuneaE C Smith
Jan 1, 1978·Nephron·G H MayorD D Makdani
Jun 16, 1977·The New England Journal of Medicine·W D KaehnyA C Alfrey
Jan 1, 1977·Nephron·J H BallD S Madison
Aug 1, 1977·Analytica Chimica Acta·F J Langmyhr, D L Tsalev
Jan 22, 1976·The New England Journal of Medicine·A C AlfreyW D Kaehny
Jun 1, 1976·Analytical Chemistry·A J BlotckyR R Recker
Mar 11, 1972·Lancet·G M BerlyneG M Danovitch
Sep 5, 1970·Lancet·G M BerlyneG R Gilmore
Jul 1, 1972·Analytical Chemistry·S S KrishnanD R Crapper
Feb 1, 1974·The Journal of Clinical Investigation·A I Arieff, S G Massry
Oct 1, 1962·British Journal of Industrial Medicine·A I MCLAUGHLINR OWEN

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.