Factors affecting use of the Doppler-determined time from flow onset to maximal pulmonary artery velocity for measurement of pulmonary artery pressure in children

The American Journal of Cardiology
G A SerwerB E Armstrong

Abstract

Measurement of the time from onset to maximal or peak velocity (TPV) of pulmonary artery (PA) flow has been proposed as a noninvasive means of determining PA pressure. The effects of age, heart rate, increased PA pressure and flow, pulmonary valve obstruction and altered PA vascular resistance on this measurement were evaluated. In 84 children, aged 1 day to 18 years, TPV was measured using continuous-wave Doppler echocardiography. The children were separated into 3 groups. Group I (n = 33) consisted of children with no cardiovascular abnormalities. Group II (n = 33) consisted of children with a variety of cardiovascular diseases producing varying PA pressures and flows. Group III (n = 18) consisted of children who had valvular pulmonic stenosis with PA to right ventricular gradients greater than 40 mm Hg. Doppler studies of group II and III patients were performed in conjunction with measurement of PA pressures and flows at the time of cardiac catheterization. In group I TPV showed a significant negative linear correlation with heart rate (r = -0.86, p less than 0.001). The ratio of observed TPV to predicted TPV (TPVN) determined using the regression equation for TPV vs heart rate or TPV/TPVN was heart rate- and age-independen...Continue Reading

References

Jul 1, 1971·Circulation Research·S R Reuben
Apr 1, 1984·The American Journal of Cardiology·D KosturakisC Loeber

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Citations

Mar 1, 1990·Journal of Clinical Ultrasound : JCU·M van de BorM E Sims
Jan 1, 1987·Cardiovascular and Interventional Radiology·S D Colan
Aug 1, 1988·Journal of the American College of Cardiology·M J CooperN H Silverman
Dec 20, 2000·Ultrasound in Medicine & Biology·C K PhoonD H Turnbull
Jan 1, 1990·Acta paediatrica Scandinavica·F J WaltherM Ebrahimi
Apr 1, 1991·Archives of Disease in Childhood·J R SkinnerE N Hey
Jul 1, 1991·Archives of Disease in Childhood·N J Evans, L N Archer
Mar 1, 1993·Archives of Disease in Childhood·A B Gill, A M Weindling
Aug 1, 1993·Archives of Disease in Childhood·J R SkinnerS Hunter
Jan 1, 1994·Archives of Disease in Childhood. Fetal and Neonatal Edition·N Evans
Mar 1, 1994·Archives of Disease in Childhood. Fetal and Neonatal Edition·D FitzgeraldD Henderson-Smart
Jan 1, 1995·Archives of Disease in Childhood. Fetal and Neonatal Edition·A BenatarM Silverman
Jan 1, 1995·Archives of Disease in Childhood. Fetal and Neonatal Edition·A B Gill, A M Weindling
May 1, 1995·Archives of Disease in Childhood. Fetal and Neonatal Edition·A H Hamdan, N J Shaw
Jul 1, 1997·Archives of Disease in Childhood. Fetal and Neonatal Edition·B H SuM Yanagisawa
Jan 1, 1989·Journal of Perinatal Medicine·T HataM Kitao
Sep 1, 1991·American Journal of Obstetrics and Gynecology·K van der MoorenJ W Wladimiroff
May 5, 2012·Pulmonary Circulation·Thibaud DamyBrigitte Fauroux
Sep 14, 2012·International Journal of Clinical Practice. Supplement·Maya GuglinRen Chen
Sep 20, 2016·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Philip T LevyGautam K Singh
Jun 1, 1987·American Heart Journal·W F GraettingerW F Voyles
Feb 12, 2017·Geriatrics & Gerontology International·Ke ZhouDavid Matchar
Feb 16, 2019·Current Treatment Options in Cardiovascular Medicine·Aura A Sanchez Mejia, Nathan J Rodgers

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