Abstract
While most children with cancer survive their initial disease, cancer therapy places them at risk for late effects (LE). Knowledge of their diagnosis, treatment, and LE risk may motivate survivors to attend long-term follow-up care. The aims of this study were to examine knowledge of cancer history and future risks, and to identify factors associated with such knowledge, in a cohort of childhood cancer survivors. Survivors (i.e., patients finished cancer treatment, regardless of time since completion) aged 15 to 26 years from three Canadian cancer centers were invited to complete a questionnaire that assessed knowledge of cancer history and potential LE of treatments, including five specific LE known to have considerable long-term health impact. Clinical data were extracted from hospital records and used to validate participants' answers. Of 250 participants, 16 (6%) were unable to name their cancer, 79 (32%) had partial or no knowledge of their therapy, and 83 (33%) were unaware of at least some of their risks for LE. Decreasing age (OR for increase in age = 1.2 (1.1-1.4)), having had a renal tumor compared to leukemia (OR = 0.3 (0.1-0.9)), and lacking knowledge about treatment (OR = 0.4 (0.2-0.9)) were associated with lack of...Continue Reading
References
Mar 1, 1989·Annals of Internal Medicine·J ByrneJ J Mulvihill
Dec 1, 1996·Journal of Clinical Epidemiology·P PeduzziA R Feinstein
Feb 22, 2001·Journal of Pediatric Psychology·V L TycG Crockett
Jul 4, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A C MertensL L Robison
Apr 10, 2002·JAMA : the Journal of the American Medical Association·Nina S Kadan-LottickAnn C Mertens
Jul 13, 2002·Medical and Pediatric Oncology·Melissa M HudsonP Hinds
May 16, 2003·Current Problems in Cancer·Kevin C Oeffinger
Sep 25, 2003·JAMA : the Journal of the American Medical Association·Melissa M HudsonUNKNOWN Childhood Cancer Survivor Study Investigators
Feb 11, 2004·Cancer·Brad J ZebrackKevin C Oeffinger
Apr 1, 2004·Annals of Family Medicine·Kevin C OeffingerLeslie L Robison
May 6, 2004·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Lisa Bashore
Feb 16, 2005·Cancer·Eva Steliarova-FoucherPeter Kaatsch
Oct 13, 2006·The New England Journal of Medicine·Kevin C OeffingerUNKNOWN Childhood Cancer Survivor Study
Apr 12, 2007·Pediatric Blood & Cancer·Branlyn E WerbaAnna T Meadows
Jan 30, 2009·JAMA : the Journal of the American Medical Association·Kevin C OeffingerLeslie L Robison
Dec 30, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Tara O HendersonChristopher K Daugherty
May 28, 2010·Cancer Causes & Control : CCC·Stephanie M SmithKevin C Oeffinger
Oct 6, 2010·Annals of Internal Medicine·Paul Craig NathanKevin Charles Oeffinger
Jan 26, 2011·Acta Oncologica·Siri L HessSophie D Fosså
May 20, 2011·Cancer·Paul C NathanMelissa M Hudson
Oct 20, 2011·Child: Care, Health and Development·L A SchwartzJ P Ginsberg
Mar 9, 2013·Journal of Cancer Survivorship : Research and Practice·Paul Craig NathanTara Olive Henderson
Jun 13, 2013·JAMA : the Journal of the American Medical Association·Melissa M HudsonLeslie L Robison
Feb 1, 2014·Clinical Journal of Oncology Nursing·Carrie Tompkins Stricker, Michele O'Brien
Jul 24, 2014·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Anne F KlassenPaul C Nathan
Nov 5, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Melissa M HudsonCheryl L Cox
Sep 1, 2013·Journal of Adolescent and Young Adult Oncology·Zahava R S Rosenberg-YungerPaul C Nathan
Citations
Feb 3, 2016·Journal of Cancer Survivorship : Research and Practice·A Fuchsia HowardArminee Kazanjian
Apr 6, 2016·Frontiers in Psychology·Marianna MasieroGabriella Pravettoni
Jul 28, 2016·Pediatric Blood & Cancer·Lisa B KenneySusan M Fernandes
Apr 4, 2017·Pediatric Blood & Cancer·Stéphane DucassouSophie Ansoborlo
Apr 18, 2018·Cancer·Jordan Gilleland MarchakLillian R Meacham
Dec 10, 2017·Journal of Cancer Survivorship : Research and Practice·A Fuchsia HowardKaren Goddard
May 10, 2018·Psycho-oncology·Jennifer WhiteJanine Giese-Davis
Nov 3, 2017·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Joanne QuillenWendy Hobbie
Jun 26, 2018·Cancer·Todd M GibsonLeslie L Robison
Apr 27, 2018·Pediatric Blood & Cancer·Jeffrey S KarstKristin M Bingen
Jan 10, 2019·Journal of Pediatric Psychology·Jennifer L LeeJordan Gilleland Marchak
Mar 19, 2020·Journal of Pediatric Psychology·Courtney LynnJordan Gilleland-Marchak
May 5, 2020·Cancer·Katie A GreenzangJennifer W Mack
Jul 28, 2019·Journal of Cancer Survivorship : Research and Practice·Jacqueline N CasillasDeborah L Estrin
Aug 28, 2020·JMIR Research Protocols·Sibylle DenzlerKatrin Scheinemann
Sep 11, 2019·Pediatric Blood & Cancer·Sobenna A GeorgeLillian R Meacham
Apr 25, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Patricia MurphyRobert Goldsby
Sep 15, 2020·Cardio-Oncology·Claire C ConleySherry-Ann Brown
Oct 5, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·A V MellblomHanne C Lie
Oct 28, 2020·CA: a Cancer Journal for Clinicians·Nicole L StoutJulie K Silver
Nov 7, 2020·Journal of Cancer Survivorship : Research and Practice·Morven C BrownLinda Sharp
Jun 9, 2021·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Lok Sum YangYin Ting Cheung
Nov 30, 2021·Pediatric Blood & Cancer·Kendall CarpenterKatie A Greenzang
Sep 1, 2021·Pediatrics·Melissa M HudsonUNKNOWN SECTION ON HEMATOLOGY/ONCOLOGY, CHILDREN’S ONCOLOGY GROUP, AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY