Factors associated with completion of bowel cancer screening and the potential effects of simplifying the screening test algorithm

British Journal of Cancer
B KearnsJ Chilcott

Abstract

The primary colorectal cancer screening test in England is a guaiac faecal occult blood test (gFOBt). The NHS Bowel Cancer Screening Programme (BCSP) interprets tests on six samples on up to three test kits to determine a definitive positive or negative result. However, the test algorithm fails to achieve a definitive result for a significant number of participants because they do not comply with the programme requirements. This study identifies factors associated with failed compliance and modifications to the screening algorithm that will improve the clinical effectiveness of the screening programme. The BCSP Southern Hub data for screening episodes started in 2006-2012 were analysed for participants aged 60-69 years. The variables included age, sex, level of deprivation, gFOBt results and clinical outcome. The data set included 1,409,335 screening episodes; 95.08% of participants had a definitively normal result on kit 1 (no positive spots). Among participants asked to complete a second or third gFOBt, 5.10% and 4.65%, respectively, failed to return a valid kit. Among participants referred for follow up, 13.80% did not comply. Older age was associated with compliance at repeat testing, but non-compliance at follow up. Increa...Continue Reading

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Citations

May 25, 2016·Journal of Medical Screening·Andrew A PlumbChristian von Wagner
Jul 20, 2018·Techniques in Coloproctology·Stella NikolaouChristos Kontovounisios
Nov 15, 2019·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·S HoeckI De Brabander
Feb 11, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·S BoschN K H de Boer

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