Factors associated with death 1 year after lower extremity bypass in Northern New England

Journal of Vascular Surgery
Philip P GoodneyVascular Study Group of Northern New England

Abstract

Using 30-day operative mortality reported with lower extremity bypass (LEB) in preoperative decision making may underestimate the actual death rate encountered before patients have truly recovered from surgery, especially in elderly, debilitated patients with significant tissue loss. Therefore, we examined preoperative, patient-level risk factors that predict survival within the first year following LEB. Using our regional quality improvement initiative in 11 hospitals in Northern New England, we studied 2306 LEB procedures performed in 2031 patients between January 2003 and December 2007. Sixty surgeons contributed to our database, and over 100 demographic and clinical variables were abstracted by trained researchers. Cox proportional hazards models were used to generate hazard ratios (HR) and surrounding 95% confidence intervals (CI) for our combined outcome measure of death occurring within the first year postoperatively. We found that within our cohort of 2306 bypass procedures, 11% of patients died within 1 year of surgery (2% prior to discharge, 9% prior to 1-year follow-up). We identified six preoperative patient characteristics associated with higher risk of death in multivariate analysis: congestive heart failure (HR 1...Continue Reading

References

May 23, 2000·Journal of Quality in Clinical Practice·I A ScottM J West
Jan 22, 2002·Pediatric Pulmonology·Gerald T O'ConnorUNKNOWN Northern New England Cystic Fibrosis Consortium
Dec 2, 2005·Statistics in Medicine·Laura AntoliniElia Biganzoli
Feb 16, 2006·Journal of Vascular Surgery·Roman NowygrodK Craig Kent
May 5, 2006·The New England Journal of Medicine·Alan T Hirsch
Jul 1, 2008·Journal of Vascular Surgery·Philip P GoodneyUNKNOWN Vascular Study Group of Northern New England
Jun 6, 2009·Journal of Vascular Surgery·Philip P GoodneyUNKNOWN Vascular Study Group of Northern New England

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Citations

Aug 9, 2015·Journal of Vascular Surgery·John M FallonUNKNOWN Vascular Study Group of New England
Mar 29, 2013·Journal of the American College of Surgeons·Tze-Woei TanUNKNOWN Vascular Study Group of New England
Oct 29, 2011·Journal of Cardiothoracic and Vascular Anesthesia·Michael MazzeffiBrigid C Flynn
Aug 9, 2011·Annals of Vascular Surgery·Vivek K MoitraJohn E Ellis
Sep 13, 2011·Current Problems in Surgery·Michael E ZenilmanJonathan C Berger
Dec 30, 2014·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·S VirtanenUNKNOWN BAROSLEEP Study Group
May 30, 2013·Journal of Vascular Surgery·Donald T BarilUNKNOWN Vascular Study Group of New England
Jul 29, 2015·Journal of Vascular Surgery·Luke VierthalerUNKNOWN Vascular Study Group of New England
May 4, 2013·Annals of Vascular Diseases·Hisao MasakiKazuo Tanemoto
Oct 10, 2014·Annals of Vascular Diseases·Hisao MasakiKazuo Tanemoto
May 1, 2012·Journal of Vascular Surgery·Jack L CronenwettRichard P Cambria
Feb 22, 2011·Journal of Vascular Surgery·Philip P GoodneyUNKNOWN Vascular Study Group of New England
Jan 25, 2013·Journal of Vascular Surgery·Michael S Conte
May 3, 2016·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·P Marqués de MarinoF J Serrano Hernando
Dec 28, 2016·Clinical Cardiology·Mislav VrsalovicMilan Milosevic
Jul 7, 2015·Vascular and Endovascular Surgery·Sukgu M HanJade Hiramoto
Feb 22, 2012·Circulation·Alan T HirschUNKNOWN Council on Epidemiology and Prevention
May 13, 2010·Current Treatment Options in Cardiovascular Medicine·Andres Schanzer, Michael S Conte
May 19, 2020·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Shin OkamotoToshiaki Mano
Jan 7, 2017·Annals of Surgery·Jason T WisemanK Craig Kent

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