PMID: 28525697Jan 1, 2016Paper

Factors associated with development atrial fibrillation after coronary artery bypass graft in elderly patients with coronary artery disease

Advances in Gerontology = Uspekhi Gerontologii
O A Rubanenko

Abstract

A total of 81 patients with coronary artery disease (CAD) who underwent coronary artery bypass graft (CABG) were enrolled in the study. Patients were divided into 2 groups: Group 1 - without postoperative atrial fibrillation (POAF) (59 patients, 74,6 % men, mean age 65,8±4 years), Group 2 - with early new-onset AF after CABG (22 patients, 90,9 % men, mean age of 67,7±5,4 years). Interleukin (IL)-6, IL-8, IL-10, C-reactive protein (CRP), fibrinogen, superoxide dismutase (SOD), troponin I were studied. During the observation period AF occurred in 27,2 % cases, an average of 4,9±3,8 days after surgery. In the postoperative period were significantly higher in group 2 left atrium (LA) (43,9±3,4 vs. 37,6±3,9 mm, p<0,001), IL-6 (72,7±60,8 vs. 38,0±34,6 pg/ml, p=0,04), IL-8 (11,9±6,0 vs. 7,7±5,4 pg/ml, p=0,01), SOD (2 462,0±2 029,3 vs. 1 515,0±1 292,9 units/g, p=0,04) when compared with group 1. The multivariate analysis showed that the odds ratio for AF development in postoperative period for LA more than 39 mm was 2,1 (95 % CI 1,2-3,8, p=0,0004), IL-6 levels more than 65,18 pg/ml - 1,4 (95 % CI 1,1-2,7, p=0,009), IL-8 levels more than 9,67 pg/ml - 1,2 (95 % CI 1,1-3,7, p=0,009), SOD more than 2948 units/g -1,1 (95 % CI 1,01-2,9, p=0,...Continue Reading

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.