PMID: 8583020Aug 1, 1995Paper

Factors associated with different responses to periodontal therapy

Journal of Clinical Periodontology
A D HaffajeeS S Socransky

Abstract

In a study of the efficacy of modified Widman flap surgery and scaling and root planning accompanied by 1 of 4 systemic adjunctive agents, Augmentin, tetracycline, ibuprofen or placebo, it was observed that subjects differed in their response to therapy. The difference was only partially accounted for by the adjunctive agent employed. The purpose of the present investigation was to examine clinical and microbiological features in subjects who showed different levels of attachment change post-therapy. 40 subjects were subset into 3 groups based on mean attachment level change post-therapy. 10 poor response subjects showed mean attachment loss; 19 moderate response subjects showed mean attachment gain between 0.02-0.5 mm and 11 good response subjects showed a mean gain of attachment > 0.5 mm. Clinical parameters were measured at 6 sites per tooth both pre- and post-therapy. Microbiological samples were taken from the mesial aspect of each tooth and evaluated individually for their content of 14 subgingival taxa using a colony lift method and DNA probes. % of sites colonized by each species was computed for each subject both pre- and post-therapy. Significant differences were observed among treatment response groups for mean probi...Continue Reading

References

May 1, 1979·Journal of Periodontology·J W KnowlesS P Ramfjord
Feb 1, 1976·Journal of Clinical Periodontology·B RoslingJ Lindhe
Feb 1, 1992·Oral Microbiology and Immunology·M GunaratnamA D Haffajee
May 1, 1988·Journal of Clinical Periodontology·J L DzinkA D Haffajee
May 1, 1983·Journal of Clinical Periodontology·A D HaffajeeJ M Goodson
Jul 1, 1982·Journal of Clinical Periodontology·J LindheE Westfelt
May 1, 1981·Journal of Periodontology·B L PihlstromR B McHugh
Jun 1, 1994·Periodontology 2000·A D Haffajee, S S Socransky

❮ Previous
Next ❯

Citations

Aug 1, 1997·Journal of Clinical Periodontology·A J van WinkelhoffU van der Velden
Jan 27, 1998·Journal of Clinical Periodontology·B von Troil-LindénS Asikainen
Feb 1, 1996·Periodontology 2000·A J van WinkelhoffJ Slots
Aug 4, 2012·Journal of Applied Oral Science : Revista FOB·Geisla Mary Silva SoaresMagda Feres
Nov 1, 1996·Annals of Periodontology·J J Zambon
Feb 20, 2004·Annals of Periodontology·Anne D HaffajeeJohn C Gunsolley
Feb 20, 2004·Annals of Periodontology·Max A Listgarten, Peter M Loomer
Jun 12, 1998·Journal of Periodontology·E E MachteiR J Genco
May 7, 2002·Journal of Periodontology·John R ElterJames D Bader
Sep 1, 2005·Journal of Clinical Periodontology·Ian NeedlemanJean Pimlott
Apr 25, 2009·Periodontology 2000·Luciana M Shaddox, Clay Walker
Apr 12, 2000·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·W J Loesche
Apr 29, 1998·Journal of Periodontal Research·A C TannerR L Kent
May 16, 2002·Periodontology 2000·Gregor J PetersilkaThomas F Flemmig

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.