Factors associated with discharge lipid-lowering drug prescription in patients hospitalized for coronary artery disease (from the Get With the Guidelines database)

The American Journal of Cardiology
Nancy M AlbertGregg C Fonarow

Abstract

Lipid-lowering therapy prevents morbidity and mortality in patients with coronary artery disease (CAD), but little is known regarding ordering practices in patients hospitalized with CAD events. Patients at participating hospitals of Get with The Guidelines-CAD, a hospital performance improvement program, were entered into a registry. Factors associated with discharge lipid-lowering therapy prescription were identified and the effect of in-hospital low-density lipoprotein cholesterol measurement on therapy prescription was evaluated. A total of 98,880 patients were enrolled at 405 hospitals. At discharge, lipid-lowering therapy was prescribed in 84.7% of patients and was associated with percutaneous coronary intervention and angiotensin-converting enzyme inhibitor, aspirin, and beta-blocker therapies at discharge, but not cardiac rehabilitation referral or coronary artery bypass grafting (all p<0.0001). After adjustment for patient characteristics, men were more likely (odds ratio [OR] 1.23, 95% confidence interval [CI] 1.18 to 1.29; p<0.0001) and patients with heart failure were less likely to be prescribed lipid-lowering therapy (OR 0.64, 95% CI 0.59 to 0.69, p<0.0001). Patients who had low-density lipoprotein cholesterol mea...Continue Reading

References

Nov 30, 2002·Lancet·James ShepherdUNKNOWN PROSPER study group. PROspective Study of Pravastatin in the Elderly at Risk
Mar 28, 2003·American Heart Journal·Ewurabena SimpsonLouise Pilote
Oct 4, 2005·Journal of the American College of Cardiology·Kim A EagleUNKNOWN American College of Cardiology Foundation (Bethesda, Maryland) Guidelines Applied in Practice Steering committee
Aug 5, 2006·European Heart Journal·Kausik K RayUNKNOWN PROVE IT-TIMI 22 Investigators

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Citations

Apr 1, 2010·Journal of Clinical Lipidology·Jennifer G RobinsonHelen Petrovich
Aug 27, 2010·Journal of Evaluation in Clinical Practice·Arden R BarryKaren G Lee
Apr 20, 2012·European Journal of Preventive Cardiology·Marie Therese CooneyIan Graham

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