Factors associated with disease-specific survival of patients with non-small cell lung cancer

Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Mirian Carvalho de SouzaAna Glória Godoi Vasconcelos


Lung cancer is a global public health problem and is associated with high mortality. Lung cancer could be largely avoided by reducing the prevalence of smoking. The objective of this study was to analyze the effects of social, behavioral, and clinical factors on the survival time of patients with non-small cell lung cancer treated at Cancer Hospital I of the José Alencar Gomes da Silva National Cancer Institute, located in the city of Rio de Janeiro, Brazil, between 2000 and 2003. This was a retrospective hospital cohort study involving 1,194 patients. The 60-month disease-specific survival probabilities were calculated with the Kaplan-Meier method for three stage groups. The importance of the studied factors was assessed with a hierarchical theoretical model after adjustment by Cox multiple regression. The estimated 60-month specific-disease lethality rate was 86.0%. The 60-month disease-specific survival probability ranged from 25.0% (stages I/II) to 2.5% (stage IV). The performance status, the intention to treat, and the initial treatment modality were the major prognostic factors identified in the study population. In this cohort of patients, the disease-specific survival probabilities were extremely low. We identified no f...Continue Reading


Feb 1, 1997·International Journal of Epidemiology·C G VictoraM T Olinto
Sep 13, 2002·Chest·Michael D BrundageWilliam J Mackillop
Aug 24, 2007·The Lancet Oncology·Arduino VerdecchiaEUROCARE-4 Working Group
Apr 1, 2010·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Tomoya KawaguchiSai-Hong Ignatius Ou
May 26, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J C SoriaT Le Chevalier
Nov 4, 2011·Nature Reviews. Clinical Oncology·Vincent T DeVita
Nov 8, 2011·Clinics in Chest Medicine·William D Travis
Nov 13, 2014·Revista brasileira de epidemiologia = Brazilian journal of epidemiology·Luiz Henrique de Lima AraujoCarlos Gil Ferreira


Oct 14, 2017·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Lei WangJu Wang
Jan 18, 2018·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Caio Júlio Cesar Dos Santos Fernandes

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Self Care (Rehabilitation)
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