Factors Associated With Health-Related Quality of Life in Medically and Surgically Treated Patients With Glaucoma

JAMA Ophthalmology
Cheryl L KhannaJonathan M Holmes

Abstract

Health-related quality of life (HRQOL) is often reduced with glaucoma, but associated factors are poorly understood. To determine factors associated with reduced HRQOL in medically and surgically treated patients with glaucoma. Prospective cohort study at a tertiary referral glaucoma practice, with 160 consecutive, prospectively enrolled medically or surgically treated adult patients with glaucoma. All patients completed 2 HRQOL questionnaires (the 25-item National Eye Institute Visual Function Questionnaire and the Adult Strabismus-20 questionnaire [AS-20]). Thirty-six patients had undergone glaucoma drainage device surgery, 51 underwent trabeculectomy, and 73 were medically treated. Factors considered for association with HRQOL in multiple regression analyses were age, sex, best-eye and worst-eye mean deviation on Humphrey visual fields, treatment modality, best-eye and worst-eye visual acuity, and diplopia. The mean (SD) age of participants was 69 (13) years, 63% were female, 97% were white, 93% were not Hispanic, and the mean deviation (SD) was -13 (10) dB. Reduced HRQOL was associated with worse diplopia (Diplopia Questionnaire score) on 6 subscales (range of partial r2 [rp2], 0.207-0.069). Reduced HRQOL was associated wit...Continue Reading

Citations

May 29, 2019·Ocular Immunology and Inflammation·Ruy Felippe Brito Gonçalves MissakaJoyce Hisae Yamamoto
Jun 6, 2018·International Ophthalmology Clinics·Kristin Schmid Biggerstaff, Albert Lin
Dec 18, 2020·The British Journal of Ophthalmology·Khin P KilgoreCheryl L Khanna
Apr 27, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Elena ScherrerFrank Bochmann

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