Factors associated with hospitalisation among people with Parkinson's disease - A systematic review and meta-analysis

Parkinsonism & Related Disorders
Olaitan OkunoyeAnette Schrag

Abstract

Parkinson's disease (PD) is associated with an increased risk of admission to hospital, however data on the main reasons for admission is lacking. Our objective was to determine the pooled prevalence of the most common factors leading to admissions among people with Parkinson's disease. MA systematic literature search was conducted in 11 electronic databases. We included all studies providing reasons for admissions among PD patients without restrictions to diagnostic criteria of PD, language or year of study. In the included studies, methodological quality, publication bias and heterogeneity were assessed. Meta-analysis was performed using random-effects models to calculate the pooled estimates of the identified top factors that lead to admission among people with PD. A total of 7283 studies were identified of which nine studies including 7162 people with PD were included in this review. There was a high degree of heterogeneity between studies regarding reasons for hospitalisation. The pooled prevalence of the topmost reasons for hospitalisation among people with PD was 22%(95%CI 16.0%-30.0%) for infections (mainly urinary tract infections and pneumonia); 19%(95%CI 13.0%-27.0%) for worsening motor manifestations of PD; 18%(95%C...Continue Reading

Citations

Apr 30, 2020·Journal of Movement Disorders·Roongroj BhidayasiriSun-Ju Chung
Aug 14, 2020·Journal of Clinical Medicine·Tino PrellTobias Mai
Oct 14, 2020·Parkinsonism & Related Disorders· Indu Subramanian, Christina L Vaughan
Feb 10, 2021·The European Journal of Neuroscience·Gabriel Antonio Gazziero MoracaLilian Teresa Bucken Gobbi
Apr 17, 2021·Annals of Medicine·Elisa MenozziAnthony H V Schapira
Jul 13, 2021·Journal of Parkinson's Disease·Sarah FearnChristopher Kipps
Jul 29, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ekawat VichayanratJalesh N Panicker
Jul 29, 2021·Journal of Movement Disorders·Yue Hui LauNorlinah Mohamed Ibrahim

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