Factors associated with long-term functional outcomes and psychological sequelae in Guillain-Barre syndrome.

Journal of Neurology
F KhanA Bhasker

Abstract

To examine factors impacting long-term health-related outcomes in survivors of Guillain-Barre syndrome (GBS). Seventy-six consecutive patients with definite GBS admitted to the Royal Melbourne Hospital (1996-2009) were reviewed in the neurorehabilitation clinics. They underwent a structured interview designed to assess the impact of GBS on their current activity and restriction in participation using validated questionnaires: Functional Independence Measure (FIM), Perceived Impact of Problem Profile (PIPP) and Depression Anxiety Stress Scale (DASS). Their sociodemographic and disease severity data were obtained from the medical record. The 76 patients [60% male, mean age 56 years, median time since GBS 6 years (range 1-14 years)] showed good functional recovery (median motor FIM score 90). However, 16% reported moderate to extreme impact on their ability to participate in work, family, and social activities; and 22% substantial impact on mood, confidence and ability to live independently. More reported moderate to extreme depression (18%), anxiety (22%) and stress (17%) compared with the normative Australian population (13%). Factors associated with poorer current level of functioning and wellbeing included: females, older pati...Continue Reading

References

Apr 23, 1992·The New England Journal of Medicine·A H Ropper
Jan 1, 1990·Annals of Neurology·A K Asbury, D R Cornblath
Jan 1, 1990·Annals of Neurology·M Alter
May 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·J B WinerC Osmond
Oct 1, 1994·Muscle & Nerve·D W Zochodne
May 1, 1997·Journal of Neurology, Neurosurgery, and Psychiatry·G X JiangJ de Pedro-Cuesta
Jun 1, 1997·Journal of Neurology, Neurosurgery, and Psychiatry·R A BernsenF G van der Meché
Aug 1, 1997·Archives of Physical Medicine and Rehabilitation·J M Meythaler
Dec 13, 1997·The Journal of Infectious Diseases·R A Hughes, J H Rees
Dec 16, 1998·Current Opinion in Neurology·H P HartungJ D Pollard
Aug 14, 2001·Journal of Neurology·R A BernsenF G van der Meché
Aug 7, 2002·Journal of the Neurological Sciences·Robert A J A M BernsenFrans G A van der Meché
Jun 4, 2005·Acta Neurologica Scandinavica·Robert A J A M BernsenTheo P B M Suurmeijer
Aug 13, 2005·Journal of Neurology·A BersanoE Nobile-Orazio
Nov 8, 2005·Lancet·Richard A C Hughes, David R Cornblath
Feb 10, 2007·Neurocritical Care·S KoeppenC Weimar
Sep 14, 2007·Disability and Rehabilitation·Sibel Ozbudak Demir, Füsun Köseoğlu
Apr 30, 2008·Neurology·Amer AlshekhleeBashar Katirji
Oct 14, 2008·Lancet Neurology·Pieter A van DoornBart C Jacobs

❮ Previous
Next ❯

Citations

Nov 10, 2011·Brain : a Journal of Neurology·David Borsook
Aug 28, 2012·BMJ Open·Tarek SharsharMarie-Hélène Marcadet
Dec 5, 2012·Neuromuscular Disorders : NMD·Ingemar S J Merkies, Catharina G Faber
Sep 10, 2014·Clinical Rehabilitation·Anette ForsbergGerd Ahlström
Oct 12, 2010·The Cochrane Database of Systematic Reviews·Fary KhanLynne Turner-Stokes
May 15, 2018·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Vesna MarticZorica Stevic
Mar 22, 2016·Muscle & Nerve·Yusuf A RajaballyAndrea E Cavanna
Mar 12, 2019·Annals of Work Exposures and Health·John HansenCharles Woodlee
May 22, 2016·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Cheryl L PetersenNaveen K Bansal
Jan 11, 2012·Journal of Clinical Psychology in Medical Settings·Stephanie A Reid-Arndt, Cathy R Cox
Jul 4, 2019·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Nian-Sheng TzengWu-Chien Chien
Nov 11, 2019·Acta Neurologica Scandinavica·Gordana DjordjevicStojan Peric
Jan 31, 2020·The International Journal of Lower Extremity Wounds·Elisabetta IacopiAlberto Piaggesi
Aug 5, 2020·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Joseph N A AkanuweAloysius Niroshan Siriwardena
Mar 3, 2021·Nature Reviews. Neurology·Nowshin PapriBart C Jacobs
May 22, 2021·Journal of Clinical Neuromuscular Disease·Mallory RobertsMandip Dhamoon
May 18, 2021·Frontiers in Pharmacology·Pei ShangHong-Liang Zhang
Jul 4, 2021·Revue neurologique·M VillainJ Swendsen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved