Factors associated with longitudinal changes in B-vitamin and choline concentrations of human milk.

The American Journal of Clinical Nutrition
Mônica A BatalhaGilberto Kac

Abstract

Little is known regarding the associations between maternal factors and B-vitamin and choline concentrations in early milk and the trajectories of these vitamins during lactation. In this hypothesis-generating study, we modeled the association between maternal and offspring factors and longitudinal changes in milk B-vitamin and choline concentrations throughout lactation. A hundred women were studied in a prospective birth cohort and milk samples from 52 women were collected at 2-8 d, 76 women at 28-50 d, and 42 women at 88-119 d postpartum. Maternal dietary intake during pregnancy and lactation was assessed by an FFQ. Linear mixed-effects models with interaction terms were used to evaluate changes in milk B-vitamin and choline concentrations over time based on maternal factors and the early postpartum concentrations of these micronutrients. The women with higher early postpartum milk concentrations of niacin (βinteraction = -0.02; SE = 0.00; P < 0.001), pantothenic acid (βinteraction = -0.10; SE = 2.56; P < 0.001), vitamin B-12 (βinteraction= -0.10; SE = 0.03; P < 0.001), and choline (βinteraction= -0.90; SE = 0.18; P < 0.001) exhibited a decrease in their concentrations throughout lactation. The participants with overweight a...Continue Reading

References

Mar 1, 1995·Journal of Human Lactation : Official Journal of International Lactation Consultant Association·S E Daly, P E Hartmann
Apr 1, 1997·The American Journal of Clinical Nutrition·W C WillettL H Kushi
Jan 25, 2003·BMJ : British Medical Journal·Douglas G Altman, J Martin Bland
Dec 16, 2003·The Journal of Nutrition·Suzanne P Murphy, Lindsay H Allen
Oct 26, 2007·Experimental Biology and Medicine·Fumio Watanabe
Jun 11, 2010·The American Journal of Clinical Nutrition·Leslie M FischerSteven H Zeisel
Apr 14, 2011·The British Journal of Nutrition·Valentina LottoSimonetta Friso
Dec 14, 2011·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Jacqueline C KentCatherine P Garbin
May 1, 2011·Experimental and Therapeutic Medicine·Noriyuki YanakaNorihisa Kato
May 11, 2013·Molecular Nutrition & Food Research·Melissa B GlierAngela M Devlin
Feb 5, 2014·Food Chemistry·Daniela HampelLindsay H Allen
Mar 4, 2014·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·P BarbieriD S Sartorelli
May 9, 2014·The American Journal of Clinical Nutrition·Arve UlvikPer M Ueland
May 6, 2015·Frontiers in Genetics·Stefanía MagnúsdóttirInes Thiele
Nov 23, 2015·Annals of Epidemiology·Seungmi Yang, Jennifer A Hutcheon
Feb 13, 2016·Lancet·Cesar G VictoraUNKNOWN Lancet Breastfeeding Series Group
May 18, 2016·Advances in Nutrition·Mirella Meyer-Ficca, James B Kirkland
Aug 19, 2016·The American Journal of Clinical Nutrition·Francesca BraviMonica Ferraroni
May 31, 2018·Advances in Nutrition·Daphna K Dror, Lindsay H Allen
Oct 20, 2018·Nutrients·Alejandra M WiedemanDavid D Kitts
Mar 14, 2019·Nestlé Nutrition Institute Workshop Series·Lindsay H Allen, Daniela Hampel
May 31, 2019·Advances in Nutrition·Rafael Pérez-EscamillaEllen Piwoz
Nov 9, 2019·Advances in Nutrition·Lindsay H AllenSuzanne P Murphy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.