Factors associated with lumbar spinal stenosis in a large-scale, population-based cohort: The Wakayama Spine Study

PloS One
Takahiro MaedaMunehito Yoshida

Abstract

Patients with lumbar spinal stenosis (LSS) who have radiographically similar degrees of stenosis may not necessarily exhibit equivalent symptoms. As part of a cross-sectional study, we examined factors associated with symptomatic LSS (sLSS) in the general population of Japan. We evaluated 968 participants (men, 319; women, 649) between 2008 and 2010. Orthopedic surgery specialists diagnosed sLSS using interview results, medical examinations, and imaging findings. LSS was radiographically graded using a 4-level scale. Additionally, we examined basic anthropometry, smoking habits, alcohol consumption, ankle-brachial index values (ABI), and glycosylated hemoglobin (HbA1c) levels. We grouped patients with moderate and severe radiographic LSS, and compared the indicated factors on the basis of the presence/absence of sLSS. Data were evaluated using multiple logistic regression analyses. Radiographically, 451 participants had moderate and 288 severe stenosis. Clinically, 92 participants were diagnosed with sLSS, including 36 with moderate and 52 with severe stenosis. In the moderate stenosis group, participants with sLSS had significantly higher rates of diabetes mellitus (DM) and lower ABIs than did non-LSS participants. Although sL...Continue Reading

References

Feb 22, 2008·The New England Journal of Medicine·Jeffrey N Katz, Mitchel B Harris
Mar 8, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Mustafa SirvanciAzmi Hamzaoglu
Jun 6, 2008·Journal of Spinal Disorders & Techniques·Raphael LotanYigal Mirovsky
Sep 15, 2009·International Journal of Epidemiology·Noriko YoshimuraToru Akune
Apr 8, 2010·JAMA : the Journal of the American Medical Association·Richard A DeyoJeffrey G Jarvik
Dec 16, 2010·JAMA : the Journal of the American Medical Association·Pradeep SuriJeffrey N Katz
Jan 23, 2015·Pain Practice : the Official Journal of World Institute of Pain·Hiroyuki Yoshihara
May 15, 2015·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Miho SekiguchiShin-ichi Konno
May 12, 2016·Clinical Medicine Insights. Endocrinology and Diabetes·Leila AsadianAmirhossein Zare

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Citations

Jun 16, 2019·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Kalliopi AlpantakiAlexander Hadjipavlou
Jan 5, 2021·JOR Spine·Naomi N LeeJames L Cook
Nov 20, 2021·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jørn AaenErland Hermansen

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