Factors associated with noninvasive ventilation response in the first day of therapy in patients with hypercapnic respiratory failure.

Annals of Thoracic Medicine
Gul GurselAyse Demir

Abstract

Noninvasive ventilation (NIV) decreases mechanical ventilation indication in the early period of acute hypercapnic respiratory failure (AHcRF) and factors for success have been studied well. But, less is known about the factors influencing the NIV response in the subacute period. This study was aimed to determine the factors influencing the reduction of PaCO(2) levels within first 24 hours of therapy. NIV response was defined as reduction of PaCO(2) level below 50 mmHg within first 24 hours. Patients with AHcRF, treated with NIV, were divided into 2 groups according to this criterion; group 1 as the nonresponsive, group 2 as the responsive. The differences in NIV methods and characteristics of the two groups were evaluated and compared in this retrospective study. A total of 100 patients were included in the study; 66 of them in group 1 and 34 in group 2. No significant differences were identified between the length of NIV application and intensive care unit (ICU) stay, intubation and mortality rates, across the groups. Ninety-one percent of the patients in group 2 had received all night long NIV therapy; this was just 74% in group 1 (P=0.036). Results of multivariate analysis showed that while nocturnal application was signifi...Continue Reading

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Citations

May 3, 2014·Annals of Thoracic Medicine·Javed H KhanMohamed S Al-Hajjaj
Feb 4, 2014·Critical Care Nursing Clinics of North America·Delia E Frederick
Jan 30, 2013·Physiotherapy·K Ward
May 17, 2017·Aging Clinical and Experimental Research·Iskender KaraG Gursel
Aug 25, 2020·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Qimin ChenFeng Shen
Mar 16, 2016·Thorax·A Craig DavidsonUNKNOWN BTS Standards of Care Committee Member, British Thoracic Society/Intensive Care Society Acute Hypercapnic Respiratory Failur
Jan 21, 2020·ERJ Open Research·Craig HukinsTimothy Edwards

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