Factors associated with overweight and obesity in schizophrenia, schizoaffective and bipolar disorders

Psychiatry Research
Virginie-Anne ChouinardDost Ongür

Abstract

Evidence suggests abnormal bioenergetic status throughout the body in psychotic disorders. The present study examined predictors of elevated body mass index (BMI) across diagnostic categories of schizophrenia, schizoaffective and bipolar disorders. In a cross-sectional study, we studied demographic and clinical risk factors for overweight and obesity in a well-characterized sample of 262 inpatients and outpatients with schizophrenia (n=59), schizoaffective disorder (n=81) and bipolar I disorder (n=122). Across the three diagnostic categories, the prevalence of overweight (29.4%) and obesity (33.2%) combined was 62.6% (164/262). Logistic regression analyses, adjusted for age, sex and ethnicity, showed that schizoaffective disorder, lifetime major depressive episode, presence of prior suicide attempt, and more than 5 lifetime hospitalizations were significantly associated with BMI≥25. Patients with schizophrenia had significantly lower risk for overweight and obesity. Overall, we found that affective components of illness were associated with elevated BMI in our cross-diagnostic sample. Our results show that patients with schizoaffective disorder have a greater risk for obesity. Identifying predictors of elevated BMI in patients ...Continue Reading

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Citations

Jun 6, 2016·Journal of Affective Disorders·Zhuoxian ZhaoAntonio L Teixeira
Jun 26, 2017·Psychotherapy and Psychosomatics·Guy ChouinardMasaomi Iyo
Mar 11, 2018·Molecular Psychiatry·Virginie-Anne ChouinardDost Öngür
Aug 20, 2018·European Psychiatry : the Journal of the Association of European Psychiatrists·Adriana PalaciosJuan Pablo Méndez
Feb 14, 2020·International Journal of Psychiatry in Medicine·Hülya ErtekinYusuf Haydar Ertekin
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Jan 15, 2018·European Psychiatry : the Journal of the Association of European Psychiatrists·Mariarita CaroleoCristina Segura-Garcia
Feb 1, 2019·Frontiers in Psychiatry·Antonio VentriglioAntonello Bellomo
Nov 5, 2016·Journal of Clinical Psychopharmacology·Qiongzhen LiXiang Yang Zhang
Mar 1, 2017·Frontiers in Psychiatry·Adonis SferaMichael Cummings
Nov 28, 2020·Perspectives in Psychiatric Care·Maha KassemFrancois Kazour
Mar 30, 2021·European Psychiatry : the Journal of the Association of European Psychiatrists·Synve Hoffart LundingNils Eiel Steen
Aug 3, 2021·Journal of Clinical Pharmacology·Christopher D BrunoDavid J Greenblatt

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