Factors associated with pulmonary embolism within 72 hours of admission after trauma: a multicenter study

Journal of the American College of Surgeons
Jamie J ColemanGrace S Rozycki

Abstract

Recent studies using thromboelastography indicate that patients are at risk for hypercoagulability early after injury. Pulmonary embolism (PE) is also well known to cause significant morbidity and mortality after injury and can occur within 72 hours of admission (early PE). Despite this risk, prophylactic anticoagulation is often delayed in patients with certain injuries due to concerns about bleeding. This was a retrospective study of injured patients with a PE from 2007 to 2013 at 3 level I trauma centers. Data collected included patient demographics, injury patterns, length of stay, timing of prophylaxis for deep vein thrombosis (DVT), and diagnosis of PE. Patients with early PE (≤ 3 days) were compared with those with late PE (>3 days) using bivariate and multivariable analysis. A total of 54,964 patients were admitted to the 3 centers during the study period, and 144 (0.26%) were diagnosed with a PE. Eleven were excluded from the study due to a lack of critical data, leaving 133 patients (43% early PE). Factors associated with early PE included long bone fractures in the lower extremity and an Abbreviated Injury Score (AIS) Extremity ≥ 3. Higher Injury Severity Score, severe chest and head trauma (AIS ≥ 3), and not receivi...Continue Reading

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Citations

Nov 8, 2015·American Journal of Surgery·Rondi B GelbardRavi R Rajani
Mar 2, 2017·The Journal of Trauma and Acute Care Surgery·Stephanie A SavageTimothy H Pohlman
Apr 10, 2017·The American Journal of Emergency Medicine·Youn-Jung KimWon Young Kim
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Feb 19, 2016·The Journal of Trauma and Acute Care Surgery·Youn-Jung KimWon Young Kim
Aug 5, 2016·The Journal of Trauma and Acute Care Surgery·George A SingerEdward B Lineen
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Sep 6, 2020·The Journal of Trauma and Acute Care Surgery·Jason P HechtWendy L Wahl
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Aug 19, 2021·Chinese Journal of Traumatology = Zhonghua Chuang Shang Za Zhi·Yu-Hong Mi, Ming-Ying Xu
Nov 3, 2021·Irish Journal of Medical Science·Gerard LambeJMark Ryan

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