Factors associated with real-time RT-PCR cycle threshold values among medically attended influenza episodes

Journal of Medical Virology
Sarah SpencerBrendan Flannery

Abstract

We evaluated the cycle threshold (CT) values of 1,160 influenza A positive and 806 influenza B positive specimens from two seasons of the US Flu VE Network to identify factors associated with CT values. Low CT values (high genomic load) were associated with shorter intervals between illness onset and specimen collection, young age (ages 3-8 years old), and self-rated illness severity for both influenza A and B. Low CT values were also associated with reported fever/feverishness and age ≥65 years for influenza A.

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Citations

May 18, 2016·The Journal of Infectious Diseases·Brendan FlanneryAlicia M Fry
Mar 2, 2019·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Antonio LaluezaCarlos Lumbreras
Dec 6, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Nenad MacesicKirsten St George
Oct 28, 2020·Influenza and Other Respiratory Viruses·Ryan E MaloshEmily T Martin
Dec 31, 2020·Open Forum Infectious Diseases·Brian McKayAndreas Handel

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