Abstract
Patients with symptomatic internal carotid artery (ICA) occlusion constitute a small proportion of stroke/transient ischaemic attack patients who are at increased risk of early stroke recurrence and poor outcome. The optimal medical treatment for patients with symptomatic ICA occlusion who are ineligible for thrombolysis or thrombectomy is unknown. Consecutive patients presenting at a single center with newly diagnosed symptomatic ICA occlusion (not involving the circle of Willis) were retrospectively reviewed. Those treated with intravenous thrombolysis or intra-arterial thrombolysis/thrombectomy were excluded. Patients were divided into two groups based on whether they experienced recurrent in-hospital stroke. The selected study population (n = 33) represented a small (20.4%) proportion of all newly symptomatic carotid occlusions, who nevertheless had an elevated risk of recurrent stroke during admission (24.2%). Of the variables examined (age, gender, admission National Institutes of Health Stroke Scale score, vascular risk factors, atrial fibrillation, prior stroke/transient ischaemic attack and anticoagulation within 48 h of presentation), only anticoagulation was significantly associated with a lower risk of in-hospital r...Continue Reading
References
Dec 1, 1986·Annals of Internal Medicine·R J DukeN Bayer
May 1, 1997·Journal of Neurology·A DelckerH Wilhelm
May 2, 1998·JAMA : the Journal of the American Medical Association
Apr 19, 2000·Lancet·E BergeP M Sandset
May 3, 2002·Journal of Neurology·S H MevesT Postert
Mar 15, 2003·Stroke; a Journal of Cerebral Circulation·Mai N Nguyen-HuynhGuy Rordorf
Jul 3, 2004·Stroke; a Journal of Cerebral Circulation·Matthew L FlahertyRobert D Brown
Mar 21, 2006·NeuroImage·Paul A YushkevichGuido Gerig
Sep 13, 2006·Archives of Neurology·Christian WeimarHans-Christoph Diener
Apr 17, 2007·Lancet Neurology·Ka Sing WongUNKNOWN FISS-tris Study Investigators
Nov 13, 2008·Vascular and Endovascular Surgery·Manj S GohelAlun H Davies
Jun 17, 2010·Cardiovascular and Interventional Radiology·Raghuram LakshminarayanDuncan F Ettles
Sep 14, 2010·Annals of Vascular Surgery·Parth S ShahKapil Gopal
Jul 16, 2011·Stroke; a Journal of Cerebral Circulation·Matthew J BurkeUNKNOWN Investigators of the Registry of the Canadian Stroke Network
Nov 15, 2011·Stroke; a Journal of Cerebral Circulation·Qiao Shu WangKa Sing Lawrence Wong
Jul 1, 2010·Journal of Surgical Technique and Case Report·Sumit Som, Bernard Schanzer
Mar 9, 2013·AJNR. American Journal of Neuroradiology·A M BoersUNKNOWN MR CLEAN investigators
May 7, 2013·Lancet Neurology·William N WhiteleyPeter A G Sandercock
Jun 5, 2014·Radiology·Andrew M DemchukUNKNOWN IMS III Investigators
Dec 11, 2014·Stroke; a Journal of Cerebral Circulation·Merel J A LuitseUNKNOWN Dutch Acute Stroke Study Group
Dec 18, 2014·The New England Journal of Medicine·Olvert A BerkhemerUNKNOWN MR CLEAN Investigators
Citations
Oct 17, 2017·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A H V Schapira
Feb 13, 2018·Biomedical Reports·Baofeng XuJinlu Yu
Aug 19, 2020·Journal of Neurology·Adrien Ter SchiphorstCaroline Arquizan
Dec 4, 2019·Current Treatment Options in Cardiovascular Medicine·Kelly L Sloane, Erica C Camargo
Sep 23, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·N BoulenoirUNKNOWN MINOR-STROKE Collaborators
Sep 24, 2021·Frontiers in Neurology·Chengrui YanRong Wang