Factors associated with red blood cell transfusions in very-low-birth-weight preterm infants in Brazilian neonatal units

BMC Pediatrics
Amélia Miyashiro Nunes dos SantosBrazilian Network on Neonatal Research

Abstract

Preterm infants in neonatal intensive care units frequently receive red blood cells (RBC) transfusions due to the anemia of prematurity. A number of variables related to gestational age, severity of illness and transfusion practices adopted in the neonatal unit where the neonate was born may contribute to the prescription of RBC transfusions. This study aimed to analyse the frequency and factors associated with RBC transfusions in very-low-birth-weight preterm infants. A prospective cohort of 4283 preterm infants (gestational age: 29.9 ± 2.9 weeks; birth weight: 1084 ± 275 g) carried out at 16 university hospitals in Brazil between January 2009 and December 2011 was analysed. Factors associated with RBC transfusions were evaluated using univariate and multiple logistic regression analysis. A total of 2208 (51.6%) infants received RBC transfusions (variation per neonatal unit: 34.1% to 66.4%). RBC transfusions were significantly associated with gestational age (OR: -1.098; 95%CI: -1.12 to -1.04), SNAPPE II score (1.01; 1.00-1.02), apnea (1.69; 1.34-2.14), pulmonary hemorrhage (2.65; 1.74-4.031), need for oxygen at 28 days of life (1.56; 1.17-2.08), clinical sepsis (3.22; 2.55-4.05), necrotising enterocolitis (3.80; 2.26-6.41), g...Continue Reading

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Citations

Mar 5, 2016·Scientific Reports·Jun DuanZhichun Feng
Feb 13, 2018·Eye·Luciana TeofiliGiovanni Vento
Feb 10, 2019·Journal of Paediatrics and Child Health·Tara M CrawfordMichael J Stark
Apr 30, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·Elodie GouacheGeraldine Favrais
Nov 28, 2020·Vox Sanguinis·Andréanne VilleneuveMarisa Tucci
Feb 12, 2021·Journal of Perinatology : Official Journal of the California Perinatal Association·Angela B Hoyos, Pablo Vasquez-Hoyos
Mar 6, 2021·Journal of Perinatology : Official Journal of the California Perinatal Association·Catherine C CibulskisAmit M Mathur
Nov 19, 2021·Indian Journal of Pediatrics·Rashmi ParasharAnubhav Gupta

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Methods Mentioned

BETA
cesarean section
blood collection

Software Mentioned

SPSS

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