Factors Associated With Refusal of Intramuscular Vitamin K in Normal Newborns

Pediatrics
Jaspreet LoyalBORN investigators

Abstract

Refusal of intramuscular (IM) vitamin K administration by parents is an emerging problem. Our objective was to assess the frequency of and factors associated with refusal of IM vitamin K administration in well newborns in the United States. We determined the number of newborns admitted to well newborn units whose parents refused IM vitamin K administration in the Better Outcomes through Research for Newborns network and, in a nested patient-control study, identified factors associated with refusal of IM vitamin K administration by using a multiple logistic regression model. Of 102 878 newborns from 35 Better Outcomes through Research for Newborns sites, parents of 638 (0.6%) refused IM vitamin K administration. Frequency of refusal at individual sites varied from 0% to 2.3%. Exclusive breastfeeding (adjusted odds ratio [aOR] = 3.4; 95% confidence interval [CI]: 2.1-5.5), non-Hispanic white race and/or ethnicity (aOR = 1.7; 95% CI: 1.2-2.4), female sex (aOR = 1.6; 95% CI: 1.2-2.3), gestational age (aOR = 1.2; 95% CI: 1.1-1.4), and mother's age (aOR = 1.05; 95% CI: 1.02-1.08) were significantly associated with refusal of IM vitamin K administration. Refusal of the administration of both ocular prophylaxis and hepatitis B vaccine ...Continue Reading

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Citations

Oct 12, 2018·Pediatric Annals·Poj Lysouvakon
Jan 8, 2020·Hospital Pediatrics·Jessica H ChengLaura R Kair
Feb 6, 2020·Hospital Pediatrics·Jaspreet Loyal, Eugene D Shapiro
Jun 3, 2020·Pediatrics in Review·Alyssa Stachowiak, Lydia Furman
Nov 26, 2020·Hospital Pediatrics·Shilpi Chabra, Annika M Hofstetter
Aug 7, 2021·Clinics in Perinatology·Michelle Leff, Jaspreet Loyal
Sep 1, 2021·Hospital Pediatrics·Julia A WisniewskiAnn Kellams
Aug 13, 2021·Hospital Pediatrics·Jaspreet Loyal, Elena Aragona
Nov 23, 2021·Hospital Pediatrics·Allene PulsiferSagori Mukhopadhyay

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