Factors associated with septic complications after restorative proctocolectomy

Annals of Surgery
Ravi P KiranVictor W Fazio

Abstract

Few studies have evaluated factors that may be associated with the development of septic complications after restorative proctocolectomy. Therefore, the aim of this study is to evaluate preoperative and operative factors that might be associated with septic complications after restorative proctocolectomy. Patients developing abdominal and pelvic septic complications after restorative proctocolectomy were identified from a prospective database. Patients with subclinical leaks and ileostomy closure leak were not included in the septic complication group. A multivariable logistic regression model for sepsis was constructed using a forward stepwise selection with entry criterion of P < 0.05. From 1983 to 2007, 3233 patients (56% male) were included in the database. Eight-four percent (2597) of patients underwent proximal diversion. Two hundred patients (6.2%) developed septic complications within 3 months of restorative proctocolectomy or within 3 months of ileostomy closure. On multivariate analysis, body mass index > 30 (P = 0.02, OR = 1.77), final pathologic diagnosis of ulcerative/indeterminate colitis (P = 0.02, OR = 2) or Crohn's disease (P = 0.02, OR = 3.6), intraoperative (P = 0.02, OR = 1.6), and postoperative transfusions...Continue Reading

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Citations

May 19, 2012·Inflammatory Bowel Diseases·Pasha J NisarRavi P Kiran
Feb 15, 2011·International Journal of Colorectal Disease·Rudolf MennigenEmile Rijcken
Jan 20, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Melanie L GainsburyJames M Becker
Mar 26, 2013·Journal of Crohn's & Colitis·Vincent BillioudLaurent Peyrin-Biroulet
Jan 10, 2013·Annals of Surgery·Victor Warren FazioSean T Martin
Sep 19, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Rudolf MennigenEmile Rijcken
Dec 18, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Emre GorgunFeza Remzi
Jan 18, 2016·International Journal of Surgery·Volkan OzbenGokhan Ozuner
Jun 13, 2015·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·I HelavirtaP Aitola
Jul 2, 2014·Inflammatory Bowel Diseases·Jingjing ShermanAlexander J Greenstein
Mar 27, 2015·Inflammatory Bowel Diseases·Melissa I ChangAlexander J Greenstein
Aug 20, 2016·Inflammatory Bowel Diseases·Tamar NobelAlexander J Greenstein
Jun 8, 2011·British Journal of Nursing : BJN·Cheryl Vidall
May 3, 2018·Inflammatory Bowel Diseases·Nicholas P McKennaAmy L Lightner
Nov 11, 2017·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Fábio Guilherme CamposIvan Cecconello
Jan 14, 2011·Diseases of the Colon and Rectum·Fergal J FlemingJohn R T Monson
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Jul 9, 2020·Irish Journal of Medical Science·Kevin McKevittJohn P Burke
Mar 20, 2012·Diseases of the Colon and Rectum·E ManilichR P Kiran
Jun 22, 2020·International Journal of Surgery Case Reports·Leonidas ChardaliasIoannis Papaconstantinou
Jul 13, 2021·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Eren EsenFeza H Remzi

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