Factors associated with the distribution of fasting plasma glucose in an adult community

American Journal of Epidemiology
E Barrett-Connor

Abstract

The fasting plasma glucose (FPG) was measured in 4170 nondiabetic adult residents of a suburban California community. At all ages the median FPG in men was higher (103-107 mg/dl) than the median FPG in women (96-104 mg/dl). FPG levels correlated weakly with obesity, and male-female differences persisted after adjustment for body mass index. In women, FPG levels rose at the age of menopause and tended to be lower in sex hormone-using women, suggesting that the male-female differences were related to estrogen. The FPG rose little with age (0.7 mg/dl/decade in men; 2.0 mg/dl/decade in women) in contrast to the 6-15 mg/dl/decade increment reported for glucose tolerance tests. These data suggest that the normal range of FPG is relatively independent of age and body mass, and that the male-female differences are not sufficiently great to necessitate sex-specific standards.

Citations

May 28, 2005·Diabetes Care·Juanjuan FanElizabeth Barrett-Connor
Jan 25, 2007·Menopause : the Journal of the North American Menopause Society·Andrew J KrentzElizabeth Barrett-Connor
Mar 1, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·R A SicreeJ E Shaw
Oct 26, 2018·Circulation Research·Chee W ChiaLuigi Ferrucci
Feb 1, 1991·Diabetologia·G Tchobroutsky
May 1, 1981·American Journal of Public Health·I G Pawson, C Janes
Jan 1, 1982·Acta diabetologica latina·P Zimmet, S Whitehouse
Aug 23, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·F HosseinpanahF Azizi
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Mar 25, 2005·Diabetic Medicine : a Journal of the British Diabetic Association·S H WildF G R Fowkes
Dec 1, 1994·Diabetes/metabolism Reviews·P Valsania, P Micossi

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