Factors associated with the overall survival of elderly patients with hepatocellular carcinoma.

World Journal of Gastroenterology : WJG
Hideki FujiiTakeshi Okanoue

Abstract

To identify the factors associated with overall survival of elderly patients with hepatocellular carcinoma (HCC). A total of 286 patients with HCC (male/female: 178/108, age: 46-100 years), who were diagnosed and treated by appropriate therapeutic procedures between January 2000 and December 2010, were enrolled in this study. Patients were stratified into two groups on the basis of age: Elderly (≥ 75 years old) and non-elderly (< 75 years old). Baseline clinical characteristics as well as cumulative survival rates were then compared between the two groups. Univariate and multivariate analyses were used to identify the factors associated with prolonged overall survival of patients in each group. Cumulative survival rates in the two groups were calculated separately for each modified Japan Integrated Stage score (mJIS score) category by the Kaplan-Meier method. In addition, we compared the cumulative survival rates of elderly and non-elderly patients with good hepatic reserve capacity (≤ 2 points as per mJIS). In the elderly group, the proportion of female patients, patients with absence of hepatitis B or hepatitis C viral infection, and patients with coexisting extrahepatic comorbid illness was higher (56.8% vs 31.1%, P < 0.001;...Continue Reading

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Citations

Mar 4, 2014·Clinics and Research in Hepatology and Gastroenterology·Aikaterini MastorakiNikolaos Arkadopoulos
Feb 6, 2016·Geriatrics & Gerontology International·Akiyoshi KinoshitaHirokazu Nishino
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May 28, 2013·Journal of Hepatology·Rita GolfieriUNKNOWN European Network on Radioembolization with Yttrium-90 Microspheres (ENRY) study collaborators
Nov 20, 2016·Journal of Hepato-biliary-pancreatic Sciences·Michinori HamaokaHideki Ohdan
Nov 12, 2014·World Journal of Gastroenterology : WJG·Koichi OishiMikiya Kitamoto
Oct 12, 2019·World Journal of Hepatology·Laura Bainy Rodrigues de FreitasMário Reis Álvares-da-Silva
Nov 20, 2019·Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences·Arash SarveazadMansour Bahardoust

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