Factors determining low anterior resection syndrome after rectal cancer resection: A study in Thai patients

Asian Journal of Surgery
Patomphon EkkaratSurasak Sangkhathat

Abstract

Defective defecation function, also known as low anterior resection syndrome (LARS), is a common problem after surgical treatment of rectal cancer that has a detrimental effect on quality of life. This study aimed to look for the incidence of LARS in patients whose native rectum could not be kept and determine factors influencing major LARS. Rectal cancer patients who underwent tumor removal with mesorectal excision and colorectal anastomosis by a colorectal surgeon during the years 2004-2013 were asked to participate a structured interview using the verified version of the Low Anterior Resection Score questionnaire. Clinical parameters were analyzed against the incidence of major LARS. The cut-off anastomotic level that corresponded to the risk of major LARS was calculated by using a receiver operating characteristic curve. Anorectal physiology was compared between those with major LARS and those without LARS by anorectal manometry. This study included 129 patients (67 men and 62 women). Incidences of minor LARS (LAR score 21-29) and major LARS (LARS score ≥ 30) score 21een those with major LARS and those univariate analysis, factors associated with major LARS were extent of operation, presence of temporary ostomy, and chemora...Continue Reading

References

Sep 26, 2002·World Journal of Surgery·John Camilleri-BrennanRobert J C Steele
Jun 5, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·O O RasmussenJ Christiansen
Nov 5, 2003·Acta Oncologica·Bengt GlimeliusEva Cavallin-Ståhl
Mar 15, 2006·Diseases of the Colon and Rectum·Johan PollackAnders Mellgren
Sep 15, 2006·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R KakodkarS Nundy
Feb 13, 2007·International Journal of Colorectal Disease·C CocoA Picciocchi
Jun 21, 2007·The British Journal of Surgery·M M LangeUNKNOWN Cooperative Clinical Investigators of the Dutch Total Mesorectal Excision Trial
Jul 9, 2008·Acta Oncologica·Katrine J Emmertsen, Søren Laurberg
Jul 7, 2011·Diseases of the Colon and Rectum·Quentin DenostEric Rullier
Aug 14, 2012·Journal of Surgical Oncology·Arun KritsanasakulSurasak Sangkhathat
Apr 16, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·S BregendahlS Laurberg
May 14, 2014·Diseases of the Colon and Rectum·Therese JuulPeter Christensen
Apr 3, 2015·The British Journal of Surgery·F J HüttnerA Ulrich

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Citations

Sep 17, 2016·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R M Jiménez-RodríguezF de la Portilla
Aug 9, 2017·Annals of Surgical Oncology·Mubarika AlaviLisa J Herrinton
Aug 18, 2018·ANZ Journal of Surgery·Alexander D CroeseYik-Hong Ho
Apr 22, 2018·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·B J P HupkensT Juul
Mar 30, 2018·Annals of Surgery·Therese JuulPalle Bager
Jun 21, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Ali BohlokGabriel Liberale
Aug 10, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M van HeinsbergenJ L Konsten
Mar 11, 2020·The British Journal of Surgery·J A G van der HeijdenJ H W de Wilt
Aug 5, 2020·Current Gastroenterology Reports·Theresa H Nguyen, Reena V Chokshi
Oct 1, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Luis Miguel Jimenez-GomezManuel Armengol-Carrasco
May 15, 2019·Annals of Surgery·Therese JuulPalle Bager
Feb 6, 2020·Revista do Colégio Brasileiro de Cirurgiões·Fernanda Letícia Cavalcante MiacciNorton Luiz Nóbrega
Jan 25, 2020·Surgery Today·Makoto KosugeKatsuhiko Yanaga
Jan 26, 2021·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·George E TheodoropoulosGeorge Zografos
Apr 11, 2021·The British Journal of Surgery·J A G van der HeijdenUNKNOWN PLCRC group
Jun 20, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Ssu-Chi ChenHans Gregersen
May 26, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Sophie A PilkingtonKaren P Nugent
Jun 8, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Isaac Seow-EnEmile Kwong-Wei Tan
Jul 24, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Rui SunYi Xiao
Aug 20, 2021·International Journal of Colorectal Disease·Alfredo AnnicchiaricoPaolo Prosperi
Sep 1, 2021·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Julia K GrassDaniel R Perez

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