Factors determining recurrence in transient global amnesia

BMC Neurology
Rebecca Tynas, Peter K Panegyres

Abstract

Aetiology of transient global amnesia (TGA) remains uncertain, though many have been proposed, including ischaemic, migrainous or epileptic pathologies. We attempted to determine risk factors for TGA, as well as prognostic factors that may cause recurrence. We evaluated clinical history, family history and magnetic resonance diffusion-weighted imaging (DWI) studies of 93 prospective patients with TGA. Patients were followed from 2004 to 2016. Fifteen of 93 (16%) patients experienced a recurrence of TGA. Among precipitating events, physical activities inducing Valsalva-like manoeuvres were most common, followed by emotional stress. Eighty-four patients had possible comorbidities or risk factors for TGA, though no single risk factor was ubiquitous. Risk factors associated with recurrence were head injury (isolated vs. recurrent, 16.7% vs. 53.5%, p < 0.01), depression (isolated vs. recurrent, 15.4% vs 46.7%, p = 0.01) and family history of dementia (isolated vs. recurrent, 20.5% vs. 46.7%, p = 0.03). Of 15 patients with confirmed recurrent TGA, two developed dementia and four subjective memory impairment. DWI lesions were observed in 24 patients and were located anywhere within the hippocampus. DWI lesions were not significantl...Continue Reading

References

Feb 1, 1992·Brain : a Journal of Neurology·T P MeloH Ferro
Jan 1, 1992·European Neurology·C GandolfoA Primavera
Jul 1, 1986·Archives of Neurology·H H HingeB de Fine Olivarius
Nov 1, 1973·Archives of Neurology·E C Shuttleworth, G R Wise
May 1, 1974·Stroke; a Journal of Cerebral Circulation·N T Mathew, J S Meyer
Aug 1, 1993·Journal of Neurosurgery·A ErdemP Roth
Jul 1, 1997·Archives of Neurology·D InzitariP Marini
Aug 26, 1998·Lancet·S L Lewis
Sep 17, 2004·Journal of Neurology·Barbara BorroniAlessandro Padovani
Dec 15, 2004·Archives of Neurology·Wenyong HuangLaura Fratiglioni
May 4, 2006·Brain : a Journal of Neurology·Peggy QuinetteFrancis Eustache
Aug 26, 2006·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C AgostiA Padovani
Jul 9, 2008·Journal of Clinical and Experimental Neuropsychology·Theodor JägerMichael G Hennerici
Jun 11, 2009·Journal of Clinical Neurology·Youngsoon YangJae Hyoung Kim
Jan 1, 2013·Case Reports in Neurology·R Rhys Davies, A J Larner
Feb 12, 2014·Headache·G Dalla VoltaA Padovani
Jun 1, 2014·Journal of Computer Assisted Tomography·Haci Taner BulutHediye Pinar Gunbey

❮ Previous
Next ❯

Citations

Sep 6, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Vittorio GovoniElisa Fallica
Jan 4, 2021·Journal of Neurology·Ioannis LiampasEfthimios Dardiotis
Feb 9, 2021·Reviews in the Neurosciences·Ioannis LiampasEfthimios Dardiotis
Mar 7, 2021·Reviews in the Neurosciences·Ioannis LiampasEfthimios Dardiotis
Jun 16, 2021·Acta Neurologica Scandinavica·Jinseung KimKang Min Park
Jul 17, 2021·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Su Jin LimSang Joon Kim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.