Factors for poor prognosis of neonatal bacterial meningitis in a medical center in Northern Taiwan

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
Mu-Chun LinChe-Sheng Ho

Abstract

Bacterial meningitis has long been a severe infectious disease in neonates, as well as a leading cause of adverse outcomes. We designed this study to know the factors for poor prognosis in neonatal bacterial meningitis. We enrolled children aged less than 1 month who were admitted to Mackay Memorial Hospital from 1984 to 2008 and had culture-proven bacterial meningitis. The laboratory data and children's clinical features were recorded. The patients' outcomes were divided into four groups: death, having sequelae, complete recovery, and loss to follow-up. Patients with the outcomes of death and having sequelae were regarded as having a poor prognosis. Those who were lost to follow-up were excluded from the analysis of outcome. Multivariate analyses were performed to find the risk factors for poor prognosis. One hundred fifty-six neonates fulfilled the inclusion criteria. Among these, 96 were boys (61.5%) and 102 (65.4%) had concomitant bacteremia. Group B streptococci (39.1%) and Escherichia coli (20.1%) were the two leading pathogens. Excluding those who were lost to follow-up (4.5%), 22 of 149 patients (14.8%) died, 36 (24.2%) had sequelae, and 91 (61.1%) recovered completely. Cerebrospinal fluid (CSF) protein more than 500 mg...Continue Reading

References

Jun 1, 1990·The Journal of Pediatrics·A F RodriguezE O Mason
Aug 1, 1990·Journal of Paediatrics and Child Health·S G Anderson, G L Gilbert
Sep 2, 2000·Pediatrics·G KlingerM Perlman
Feb 24, 2001·Archives of Disease in Childhood. Fetal and Neonatal Edition·D E HoltD Harvey
Aug 3, 2001·Seminars in Neonatology : SN·R A Polin, M C Harris
Jul 11, 2003·The Journal of Infectious Diseases·Feng-Ying C LinKaren Adams
Dec 4, 2003·Pediatric Neurology·Chin-Jung ChangHsueh-Wen Chang
Sep 8, 2004·Pediatric Neurology·Chin-Jung ChangCheng-Hsien Lu
Sep 16, 2009·Pediatrics·Francesco PisaniStefano Seri
Mar 6, 2010·Pediatrics International : Official Journal of the Japan Pediatric Society·Mohammad Hasan AletayebDehdashtian Masood
Jun 18, 2010·International Journal of Pediatric Otorhinolaryngology·S CoenraadL J Hoeve
Aug 5, 2011·Indian Journal of Human Genetics·Seema LekhwaniN D Vaswani

❮ Previous
Next ❯

Citations

Nov 5, 2013·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Meng-Chin LinFu-Yuan Huang
Dec 3, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Wen-Li LinNan-Chang Chiu
Jan 14, 2012·Journal of the Chinese Medical Association : JCMA·Ming-Jie YangPeng-Hui Wang
Nov 9, 2018·Frontiers in Neurology·Mei-Hsin HsuMing-Horng Tsai
Sep 29, 2019·Pediatrics International : Official Journal of the Japan Pediatric Society·Ki Wook YunHyunju Lee
Aug 17, 2018·Experimental and Therapeutic Medicine·Bing SongLi Sun
Dec 6, 2018·Frontiers in Neurology·Dan-Hua MaoQi-Xiong Chen
Oct 19, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anne-Sophie RomainCorinne Levy

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Bacterial Meningitis (ASM)

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Bacterial Meningitis

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.

Related Papers

Tropical Medicine & International Health : TM & IH
J S FurykE Molyneux
Pediatrics International : Official Journal of the Japan Pediatric Society
Mohammad Hasan AletayebDehdashtian Masood
Pediatric Neurology
Chin-Jung ChangHsueh-Wen Chang
Journal of Infection in Developing Countries
Sultan KavuncuoğluEmine Hoşaf
© 2021 Meta ULC. All rights reserved