Factors influencing combined exposure to three indicator polychlorinated biphenyls in an adult cohort from Bolivia

Environmental Research
J P ArrebolaL A Mercado

Abstract

Polychlorinated biphenyls are persistent organic pollutants that have been used for decades in several industrial applications. Although production of polychlorinated biphenyls was restricted from the 1970s in most countries, substantial amounts remain in old equipment and buildings and they have been detected in various environmental and biological matrices. The main objective of this study was to analyze predictors of the combined exposure to three non-dioxin-like polychlorinated biphenyls (congeners 138, 153 and 180) in serum and adipose tissue from an adult cohort (n=112) living in the city of Santa Cruz de la Sierra (Bolivia) and surrounding towns/villages. A second aim was to identify modifiers that might influence the statistical associations found, using crude, partially-adjusted, and global multiple linear regression models. Main predictors of serum concentrations were occupation and fatty food consumption, while those for adipose tissue concentrations included age, smoking habit, fatty food consumption, and residence. The differences between the two matrices might be derived from their biological meaning, given that adipose tissue concentrations are an indicator of chronic exposure to polychlorinated biphenyls while s...Continue Reading

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Citations

May 17, 2013·Environmental Science and Pollution Research International·Henrieta PatayováTomáš Trnovec
Jan 15, 2015·The Science of the Total Environment·F Artacho-CordónN Olea
Mar 8, 2016·The Science of the Total Environment·Jinjian DingFangxing Yang
Aug 25, 2015·The Science of the Total Environment·M Fernández-RodríguezN Olea
Jul 10, 2021·International Journal of Hygiene and Environmental Health·Nis-Julius SontagDaniel S Drage

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