Factors influencing local recurrence after abdominoperineal resection for cancer of the rectum and rectosigmoid.

The British Journal of Surgery
A R MoossaD B Skinner

Abstract

One hundred and fifty-two patients who underwent abdominoperineal resection for cancer of the rectum and rectosigmoid are reviewed. Six physicians were selected to predict which of these patients would have a local recurrence. All information available at the end of the operation was duplicated and submitted to the observers. None of the physicians was able to predict local recurrence significantly better than random. There were 31 local recurrences, i.e. an incidence of 20-4 per cent. Low level of tumour in the rectum, local spread into perirectal fat or serosa, lymph node involvement and age below 60 years at time of operation were the only factors that were statistically related to local recurrence. The strategy for careful follow-up of patients at risk is outlined and a plea is made for a controlled trial of postoperative radiotherapy.

Citations

Sep 8, 1998·Seminars in Surgical Oncology·J N WiigO Søreide
Jan 1, 1993·Seminars in Surgical Oncology·J M JessupG Steele
Aug 1, 1987·World Journal of Surgery·J Jeekel
Sep 1, 1982·World Journal of Surgery·A M CohenC E Welch
Sep 1, 1992·Diseases of the Colon and Rectum·J S ChenH A Fan
May 2, 2001·Diseases of the Colon and Rectum·M KillingbackO F Dent
Jul 1, 1993·Diseases of the Colon and Rectum·F SafiH G Beger
Nov 1, 1992·Diseases of the Colon and Rectum·R TangH A Fan
Dec 1, 1987·Diseases of the Colon and Rectum·T BjerkesetO Søreide
Jun 1, 1989·Diseases of the Colon and Rectum·J BeynonJ Virjee
Jun 1, 1987·Diseases of the Colon and Rectum·R P Waldron, I A Donovan
Jun 1, 1985·Diseases of the Colon and Rectum·M AdloffD Thibaud
Sep 1, 1982·Diseases of the Colon and Rectum·P H Sugarbaker, S Corlew
Jul 1, 1980·Diseases of the Colon and Rectum·T Bjerkeset, O Dahl
Oct 1, 1979·Diseases of the Colon and Rectum·R D James
May 1, 1981·Diseases of the Colon and Rectum·A M CohenC E Welch
Sep 1, 1978·International Journal of Radiation Oncology, Biology, Physics·S G Gilbert
Feb 1, 1986·International Journal of Radiation Oncology, Biology, Physics·P R ThomasA Mittelman
Feb 17, 2000·Surgical Oncology·A R Miller
Jun 20, 2001·The British Journal of Surgery·T HolmB Cedermark
Apr 1, 1982·Annals of Surgery·J BoeyG B Ong
Sep 1, 1988·Annals of Surgery·F MichelassiR Chappell
Jan 1, 1992·World Journal of Surgery·F IzarN Daly
Feb 16, 2008·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·T Junginger, P Hermanek
Feb 1, 1980·International Journal of Radiation Oncology, Biology, Physics·M MohiuddinS Kramer
Jul 1, 1987·International Journal of Radiation Oncology, Biology, Physics·A VigliottiM J Oswald
Feb 1, 1986·International Journal of Radiation Oncology, Biology, Physics·L L Gunderson
Sep 1, 1988·International Journal of Radiation Oncology, Biology, Physics·R WiggenraadF E Probst-van Zuylen
May 1, 1988·International Journal of Radiation Oncology, Biology, Physics·J E Tepper
Dec 17, 2002·Clinical Colorectal Cancer·Carolyn C Compton
Feb 1, 1989·American Journal of Surgery·R T Long, R H Edwards
Mar 1, 1982·American Journal of Surgery·K Hojo, Y Koyama
Apr 1, 1980·American Journal of Surgery·C G Mixter
Dec 1, 1986·Current Problems in Surgery·E M BrickerW D Johnston
Dec 1, 1979·The Australian and New Zealand Journal of Surgery·M T PheilsJ G MacPherson
Apr 16, 1998·Seminars in Radiation Oncology·J M JessupR Bleday
Apr 1, 1978·American Journal of Surgery·J P Welch, G A Donaldson
Jun 7, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R M AnwarW Stevens
Jun 7, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R A GamagamiF Lazorthes
May 1, 2000·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland· Heriot, Kumar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.