Factors Influencing Migraine Recurrence After Infusion and Inpatient Migraine Treatment in Children and Adolescents

Headache
Katherine M Cobb-PitstickJoanne Kacperski

Abstract

To evaluate factors that influence migraine recurrence after outpatient infusion or inpatient treatment for intractable migraine. Recurrence of migraine after acute treatment in an infusion center or an inpatient setting is not well documented in children and adolescents. Given the multifactorial pathogenesis of migraines, multiple factors may influence migraine recurrence. It has been reported that treatment with steroids may reduce the risk of migraine recurrence. The efficacy of steroids as a therapeutic adjunct has not been established. Studies in the adult population have yielded conflicting results. This study is a retrospective chart review of patients presenting for treatment of an intractable migraine to the outpatient infusion unit or inpatient unit at Cincinnati Children's Hospital Medical Center (CCHMC). Data collected included: age, gender, location of treatment (outpatient, inpatient), migraine duration, diagnosis, severity, the addition of steroids to treatment protocols, and recurrence of migraine at 48 and 72 hours after discharge. Data were analyzed using Fisher's exact tests, logistic regression with backward elimination for variable selection, and least squares means slicing with associated odds ratios. Char...Continue Reading

References

Jul 16, 2005·Pediatric Annals·Marielle A Kabbouche, Steven L Linder
Oct 23, 2009·The Journal of Emergency Medicine·Frederick W FiesselerNima Majlesi

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Citations

Dec 29, 2015·Current Pain and Headache Reports·Tzu-Hsien Lai, Shuu-Jiun Wang
Mar 14, 2018·JAMA Neurology·Carlyn Patterson-Gentile, Christina L Szperka
Jul 9, 2020·Current Pain and Headache Reports·Klaus WernerAndrew D Hershey
Feb 13, 2018·Expert Review of Neurotherapeutics·Marco Antônio ArrudaMarcelo Eduardo Bigal
Nov 2, 2018·Current Neurology and Neuroscience Reports·Reena Gogia RastogiRobert Little
Jun 6, 2021·Current Neurology and Neuroscience Reports·Mohammed AlqahtaniAna Marissa Lagman-Bartolome
Aug 5, 2021·Pediatric Quality & Safety·Adam A VukovicEileen Murtagh-Kurowski

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