PMID: 9420760Jan 1, 1995Paper

Factors influencing myocardial salvage with primary angioplasty

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
J H O'KeefeR J Gibbons

Abstract

The purpose of this study was to evaluate the factors influencing the salvage of jeopardized myocardium in patients treated with primary angioplasty for acute myocardial infarction. This multicenter study involved 59 patients with acute myocardial infarction who underwent primary angioplasty without antecedent thrombolytic therapy and paired baseline (before angioplasty) and predischarge tomographic perfusion imaging by quantitative 99mTc-labeled sestamibi techniques for assessing the initial area at risk and eventual infarct size. Of the 59 patients who underwent primary angioplasty, Thrombolysis In Myocardial Infarction (TIMI) level 3 perfusion was restored in the infarct vessel in 54 patients (92%). On average, approximately one third of the left ventricular myocardial mass was initially jeopardized by the infarction in progress; eventual infarct size was 18% +/- 15% of the left ventricle; myocardial salvage was 16% +/- 17% of the left ventricle. Primary angioplasty salvaged 46% +/- 50% of initially jeopardized myocardium. Factors correlated with myocardial salvage included elapsed time from onset of pain to reperfusion, infarct location (anterior infarcts had more myocardial salvage than inferior infarcts), and residual flo...Continue Reading

References

Dec 1, 1992·Journal of the American College of Cardiology·M D CerqueiraJ W Kennedy
Jan 1, 1992·Journal of the American College of Cardiology·K C HuberR J Gibbons
Jan 11, 1992·American Heart Journal·J H O'KeefeG O Hartzler
May 1, 1991·Journal of the American College of Cardiology·T F ChristianB J Gersh
Aug 11, 1983·The New England Journal of Medicine·UNKNOWN Multicenter Postinfarction Research Group
May 6, 1982·The New England Journal of Medicine·G SanzF Navarro-López
Sep 2, 1993·The New England Journal of Medicine·UNKNOWN GUSTO investigators
Mar 11, 1993·The New England Journal of Medicine·F ZijlstraH Suryapranata

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Citations

Jul 1, 1996·European Journal of Nuclear Medicine·G Hör
Jul 14, 2005·Molecular and Cellular Biochemistry·Garrett J Gross, Samuel F Lockwood
Mar 21, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·J H O'KeefeJ Spertus
Aug 3, 2006·Journal of Interventional Cardiology·Kishore J HarjaiUNKNOWN Primary Angioplasty In Myocardial Infarction (PAMI) Investigators
Nov 13, 2001·The American Journal of Cardiology·B R BrodieUNKNOWN Stent Primary Angioplasty in Myocardial Infarction Study Group
Dec 25, 2004·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nedy BrambillaLuigi Tavazzi
Mar 25, 2005·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Ronald P CaputoPaolo Esente
Sep 1, 1995·Postgraduate Medicine·James H O'KeefeCarl J Lavie
Jun 27, 2020·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Kishore J HarjaiJames C Blankenship

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