Factors Influencing Non-albicans Candidemia: A Case-Case-Control Study

Mycopathologia
Diamantis P KofteridisGeorge Samonis

Abstract

The study identified factors predisposing to non-albicans candidemia with special interest to prior antimicrobial treatment. A retrospective, case-case-control study was performed at the University Hospital of Heraklion, Greece, from November 2007 through September 2011 including adult patients. The study had three groups. The first included 58 patients with non-albicans candidemia, the second 48 with C. albicans candidemia, while the third (control) 104 without candidemia. Each of the two candidemia groups was compared with the control using multivariate logistic regression model. The mean (SD) age of the non-albicans, the albicans and the control patients was 67 (12), 67 (18) and 59 (19) years, respectively. The most common non-albicans Candida spp. isolated were C. parapsilosis in 19 patients (33%), C. glabrata in 17 (29%) and C. tropicalis in 15 (26%). Independent risk factors for non-albicans candidemia were prior treatment with quinolones (p < 0.001), b-lactam-b-lactamase inhibitors (p = 0.011) and presence of central venous catheter (p = 0.05), while for C. albicans candidemia were prior treatment with quinolones (p < 0.001), carbapenems (p = 0.003) along with cardiac disease (p < 0.001). Neither duration of hospitalizat...Continue Reading

References

Sep 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·V J FraserW C Dunagan
May 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·G T ColeE J Anaissie
Oct 3, 1998·Antimicrobial Agents and Chemotherapy·A S OrozcoS G Filler
Aug 19, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C ViscoliF Meunier
Aug 25, 1999·Diagnostic Microbiology and Infectious Disease·A L ColomboS B Wey
Jan 30, 2004·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M A PfallerUNKNOWN International Fungal Surveillance Participant Group
Aug 13, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Hilmar WisplinghoffMichael B Edmond
Dec 24, 2004·Antimicrobial Agents and Chemotherapy·Nicole J PultzCurtis J Donskey
May 4, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Keith S KayeYehuda Carmeli
Oct 6, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Theoklis E ZaoutisChris Feudtner
Dec 16, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Brad J SpellbergJohn E Edwards
May 1, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jennifer K ChowSusan Hadley
Mar 12, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D RodríguezUNKNOWN Barcelona Candidemia Project Study Group
May 26, 2010·Antimicrobial Agents and Chemotherapy·José Garnacho-MonteroCarlos Ortiz-Leyba
Apr 29, 2011·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Hung-Wei ChiJung-Chung Lin
Feb 9, 2012·Antimicrobial Agents and Chemotherapy·Ronen Ben-AmiUNKNOWN Israeli Candidemia Study Group

❮ Previous
Next ❯

Citations

Nov 14, 2020·Mycoses·Caitlin Livia KeighleySharon C-A Chen
Dec 23, 2021·Internal Medicine Journal·Caitlin KeighleyUNKNOWN Australasian Antifungal Guidelines Steering Committee

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

Beta-lactamase Inhibitors (ASM)

Beta-lactamase inhibitors are a class of antibiotics that inhibit beta-lactamases, a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Beta-lactamase Inhibitors

Beta-lactamase inhibitors are a class of antibiotics that inhibit beta-lactamases, a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Here is the latest research.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

© 2022 Meta ULC. All rights reserved