Factors influencing outcome of kidney allografts from pretreated cadaveric donors

Archives of Surgery
S SterioffK P Offord

Abstract

A five-year retrospective analysis of patient and graft survival after initial cadaveric kidney transplantation showed that recipients of kidneys from cadaveric donors pretreated with cyclophosphamide (Cytoxan) and methylprednisolone (Medrol) had better graft survival than those patients who received nonpretreated kidneys. In patients not receiving transfusions, transplantation of a pretreated kidney improved the chances of success, with graft survival equivalent to that for patients receiving transfusions. Splenectomy was beneficial for graft survival and did not affect overall patient survival. The effect of splenectomy could not be clearly separated fro the effect of donor pretreatment.

Citations

Nov 1, 1983·American Journal of Surgery·S E OkiyeW J Johnson
Jan 8, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Roman Reindl-SchwaighoferRainer Oberbauer

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