PMID: 6110313Aug 1, 1980Paper

Factors influencing seizure duration and number of seizures applied in unilateral electroconvulsive therapy. Anaesthetics and benzodiazepines

Acta Psychiatrica Scandinavica
L S StrömgrenA Thomsen

Abstract

A certain minimum in the duration of seizures appears to be a condition for a satisfactory therapeutic effect in ECT. The aim of the present investigation is to elucidate the importance of some factors which may influence the seizure duration. In a controlled double-blind investigation with crossover, carried out on 19 patients, thiopentone and methohexitone were compared as anaesthetics for unilateral ECT. No differences were found between the anaesthetics regarding duration of seizures, number of treatments with insufficient seizures duration or amount of energy applied. Blood pressure measured after the seizure was slightly higher with thiopentone than with methohexitone and methohexitone as anaesthetic for ECT. In a retrospective investigation concerning seizure duration in unilateral ECT, patients given benzodiazepines during the treatment period were compared with patients who received no such medication. The benzodiazepine group showed shorter seizure duration, more cases with insufficient seizure duration and a need for a greater number of treatments. Benzodiazepines should be administered with caution during ECT, as they can impair the efficacy of treatments and consequently prolong the treatment period.

References

Nov 1, 1978·Comprehensive Psychiatry·B M Maletzky
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Citations

Sep 1, 1984·Canadian Anaesthetists' Society Journal·R J Marks
Jan 1, 1990·Biological Psychiatry·B H King, E H Liston
May 15, 1995·Biological Psychiatry·C E CoffeyM Aque
Apr 1, 1992·Journal of Psychiatric Research·N LoimerH R Chaudhry
Jan 1, 1995·European Psychiatry : the Journal of the Association of European Psychiatrists·M AuriacombeJ Tignol
Apr 11, 2001·Progress in Neuro-psychopharmacology & Biological Psychiatry·S M DursunM A Reveley
Sep 1, 1997·Biological Psychiatry·G PetridesA Francis
Oct 4, 2015·Nutrition Reviews·Amene SaghazadehNima Rezaei
Jul 30, 2014·Psychiatry and Clinical Neurosciences·Kazuyuki YasudaNobutaka Motohashi
May 15, 2013·Journal of Affective Disorders·Verònica GálvezMikel Urretavizcaya
Dec 1, 1991·The Australian and New Zealand Journal of Psychiatry·C A GalletlyC L Ormond
May 7, 1997·Evaluation Review·J WestphalI C Sarkar
Mar 1, 1985·Acta Psychiatrica Scandinavica·H M Standish-BarryR P Snaith
Jan 1, 1988·The British Journal of Psychiatry : the Journal of Mental Science·M Sharpe, B Andrew

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