PMID: 11920894Mar 29, 2002Paper

Factors influencing the flow rate through a surgical defect in human fetal membranes

Prenatal Diagnosis
R DevliegerJ Deprest

Abstract

In order to determine factors influencing the flow rate trough a created defect in human fetal membranes, an ex vivo set-up was used with fetal membranes collected from patients undergoing Caesarean section at term. The membranes were secured at the bottom of a plastic tube and traumatised with needles ranging from 14-26 Gauges (Ga), under a hydrostatic pressure of 10 to 20 cm H(2)O and an angle of 45 degrees or 90 degrees. The column was filled with amniotic fluid or Hartmann's solution. The duration of the puncture was 1 s or the time it takes to aspirate 10 ml through the needle. The flow rate through the defect in the fetal membranes and size of the defect were measured. The flow rate and defect size increased with increasing diameter of the needle. Increasing the pressure in the column resulted in a significant linear increase in the flow rate. Replacing the saline solution with amniotic fluid did not result in significant changes in the measured flow rates, except for the small needle size (24 Ga). Increasing the duration of the puncture did not result in increased flow rates, except for small needle size (24 Ga). These experiments suggest that needle diameter, angle of needle insertion, duration of the procedure, amnioti...Continue Reading

References

Jan 1, 1992·British Journal of Obstetrics and Gynaecology·N M FiskC H Rodeck
Mar 1, 1983·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·S G Parulekar
Mar 1, 1997·Obstetrics and Gynecology Clinics of North America·E A Reece
Apr 29, 1999·Current Opinion in Obstetrics & Gynecology·J A Deprest, E Gratacos
Sep 14, 2000·Baillière's Best Practice & Research. Clinical Obstetrics & Gynaecology·E JauniauxC H Rodeck
Sep 15, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·R DevliegerJ A Deprest

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Citations

Jul 13, 2002·Prenatal Diagnosis
Aug 17, 2010·Journal of Perinatal Medicine·Seyfettin UludagCihat Sen
Jun 2, 2011·Journal of Perinatal Medicine·Michael TchirikovHeinz Koelbl
Mar 24, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Helen K Carnaghan, Michael R Harrison
Aug 10, 2015·Journal of the Mechanical Behavior of Biomedical Materials·Michela PerriniMartin Ehrbar
May 10, 2006·American Journal of Obstetrics and Gynecology·R DevliegerJ A Deprest
Aug 17, 2012·The Cochrane Database of Systematic Reviews·Faris Mujezinovic, Zarko Alfirevic

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