Factors involved in the antibiotic treatment of cerebrospinal fluid shunt infections

Zeitschrift Für Kinderchirurgie : Organ Der Deutschen, Der Schweizerischen Und Der Osterreichischen Gesellschaft Für Kinderchirurgie = Surgery in Infancy and Childhood
R Bayston, A M Rickwood

Abstract

Fourty-four patients whose staphylococcal shunt infections were treated with antibiotics alone are reviewed retrospectively. Successful eradication of infection was achieved in 4 out of 7 patients who received intrathecal gentamicin and oral cotrimoxazole for ventriculoatrial shunt infections due to Staphylococcus albus, and in two of four patients with ventriculo-peritoneal shunt infections due to this organism who received cotrimoxazole alone, though one of these later required surgery for cystic blockage. No successes were recorded with other drugs, notably cloxacillin, and no infections due to Staphylococcus aureus were eradicated. Possible reasons for these findings are discussed with a view to developing guidelines for a prospective trial.

Citations

Jul 1, 1985·Indian Journal of Pediatrics·P Upadhyaya
May 20, 2015·Journal of Neurosurgery. Pediatrics·Mandeep S TamberUNKNOWN Pediatric Hydrocephalus Systematic Review and Evidence-Based Guidelines Task Force
Jul 12, 2018·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·C GadererU W Thomale

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