Factors Predicting a Good Symptomatic Outcome After Prostate Artery Embolisation (PAE)

Cardiovascular and Interventional Radiology
Drew MacleanTimothy Bryant

Abstract

As prostate artery embolisation (PAE) becomes an established treatment for benign prostatic obstruction, factors predicting good symptomatic outcome remain unclear. Pre-embolisation prostate size as a predictor is controversial with a handful of papers coming to conflicting conclusions. We aimed to investigate if an association existed in our patient cohort between prostate size and clinical benefit, in addition to evaluating percentage volume reduction as a predictor of symptomatic outcome following PAE. Prospective follow-up of 86 PAE patients at a single institution between June 2012 and January 2016 was conducted (mean age 64.9 years, range 54-80 years). Multiple linear regression analysis was performed to assess strength of association between clinical improvement (change in IPSS) and other variables, of any statistical correlation, through Pearson's bivariate analysis. No major procedural complications were identified and clinical success was achieved in 72.1% (n = 62) at 12 months. Initial prostate size and percentage reduction were found to have a significant association with clinical improvement. Multiple linear regression analysis (r2 = 0.48) demonstrated that percentage volume reduction at 3 months (r = 0.68, p < 0.0...Continue Reading

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Dec 4, 2019·Cardiovascular and Interventional Radiology·Francois H CornelisFrancisco Cesar Carnevale
Nov 19, 2019·Journal of Vascular and Interventional Radiology : JVIR·Georg Friedrich EnderleinTobias Franiel
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Jul 6, 2020·Seminars in Ultrasound, CT, and MR·Essam HashemMohamed Khalifa

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