Factors Predicting Arrhythmia-Related Symptoms and Health-Related Quality of Life in Patients Referred for Radiofrequency Ablation of Atrial Fibrillation: An Observational Study (the SMURF Study)

JACC. Clinical Electrophysiology
Emmanouil CharitakisHåkan Walfridsson

Abstract

The purpose of this study was to correlate the arrhythmia-related symptoms and health-related quality of life (HRQoL) in patients with atrial fibrillation (AF) who are eligible for radiofrequency ablation (RFA) with a number of objective indicators. Although the clinical consequences of AF have been studied extensively, the variation in the symptoms of patients with AF and HRQoL remains under-researched. We studied 192 patients eligible for RFA of AF referred to the University Hospital, Linköping, Sweden, between January 2012 and April 2014. The ASTA (Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia) symptom scale was used to assess arrhythmia-related symptoms in the patients. The ASTA HRQoL scale and the short-form 36 (SF-36) physical and mental components summaries (PCS and MCS) were used to express disease-specific and overall HRQoL of the patients, respectively. Anxiety, low-grade inflammation, and left atrial dilatation significantly predicted arrhythmia-related symptoms (R2 = 0.313; p < 0.001). Depression was the most important predictor of arrhythmia-specific HRQoL (standardized beta: 0 .406), and the produced model explained a significant proportion of the variation in arrhythmia-specific HRQoL (R2 = 0.51...Continue Reading

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Citations

Sep 10, 2019·Pacing and Clinical Electrophysiology : PACE·Ulla WalfridssonHåkan Walfridsson
Dec 17, 2019·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Niv Ad
Aug 25, 2020·Psychosomatic Medicine·Eusebio García-IzquierdoIgnacio Fernández-Lozano
Dec 31, 2019·Cardiology Research and Practice·Marie StridsmanUlla Walfridsson
Oct 30, 2018·Journal of the American Heart Association·Tomos E WaltersJonathan M Kalman
Aug 15, 2020·Scientific Reports·Kenji SuitaSatoshi Okumura
Dec 30, 2020·Pacing and Clinical Electrophysiology : PACE·Daniele MalaspinaGiovanni Battista Perego
Dec 17, 2021·Clinical Cardiology·Ulla WalfridssonEmmanouil Charitakis

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