Factors predicting hypocalcemia after total thyroidectomy - A retrospective cohort analysis

International Journal of Surgery
Claudius FalchSven Muller

Abstract

Hypocalcemia after total thyroidectomy is the most frequent complication resulting in prolongation of hospitalisation. Therefore we aimed to analyse clinical risk factors predictive for hypocalcemia and its long term persistence after total thyroidectomy. Retrospective analysis of patients undergoing total thyroidectomy from 2005 until 2013. Outcome measures were initial postoperative hypocalcemia defined as serum calcium below 2.0 mmol/l after total thyroidectomy within 48 h and persistent hypocalcemia defined as serum calcium below 2.0 mmol/l above six months and/or the need for additional calcium and vitamin D supplementation. Initial postoperative hypocalcemia was present in 160 of 702 patients (22.8%) with 91 patients (13%) developing symptoms. 48 patients (6.8%) had a persistent hypocalcemia above six months. Patients with an initial symptomatic postoperative hypocalcemia showed significantly more often a persistent hypocalcemia compared to asymptomatic patients with biochemical hypocalcemia (38 patients (41.8%) vs. 10 patients (14.5%), p < 0,001). In the binary logistic regression analysis, female gender (OR 2.4; CI95% 1.5-3.8), prolonged surgery time >189 min (OR 1.8; CI95% 1.2-2.6) and parathyroid reimplantation (OR 2....Continue Reading

Citations

Aug 30, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R K SaadG A E-H Fuleihan
Jun 11, 2020·The Journal of Laryngology and Otology·A E L McMurranV Kim
Mar 25, 2020·Indian Journal of Surgical Oncology·S R Priya, Chandrashekhar Dravid
Apr 10, 2020·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·David PalmhagInga-Lena Nilsson
Jan 6, 2021·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·Q A J HagdornS Velthuis
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Apr 2, 2021·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Eun Ho Eunice ChoiMark R Burge
Mar 29, 2021·International Journal of Surgery·Sam Van SlyckeNele Brusselaers

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