Factors predicting the failure of Bernese periacetabular osteotomy: a meta-regression analysis.

International Orthopaedics
Senthil Nathan SambandamWilliam A Jiranek

Abstract

There is no clear evidence regarding the outcome of Bernese periacetabular osteotomy (PAO) in different patient populations. We performed systematic meta-regression analysis of 23 eligible studies. There were 1,113 patients of which 61 patients had total hip arthroplasty (THA) (endpoint) as a result of failed Bernese PAO. Univariate analysis revealed significant correlation between THA and presence of grade 2/grade 3 arthritis, Merle de'Aubigne score (MDS), Harris hip score and Tonnis angle, change in lateral centre edge (LCE) angle, late proximal femoral osteotomies, and heterotrophic ossification (HO) resection. Multivariate analysis showed that the odds of having THA increases with grade 2/grade 3 osteoarthritis (3.36 times), joint penetration (3.12 times), low preoperative MDS (1.59 times), late PFO (1.59 times), presence of preoperative subluxation (1.22 times), previous hip operations (1.14 times), and concomitant PFO (1.09 times). In the absence of randomised controlled studies, the findings of this analysis can help the surgeon to make treatment decisions.

Associated Clinical Trials

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Citations

Aug 24, 2010·AJR. American Journal of Roentgenology·Richard Kijowski
Aug 25, 2012·Radiology·Reto SutterChristian W A Pfirrmann
Feb 7, 2013·International Orthopaedics·Ryo MoriMitsuo Ochi
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May 8, 2009·Clinical Orthopaedics and Related Research·Michael B MillisJohn C Clohisy
Jun 21, 2013·Journal of Pediatric Orthopedics·Ira Zaltz
Dec 27, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Meng XuYu Sun
Dec 5, 2014·The Journal of Bone and Joint Surgery. American Volume·Yukiharu HasegawaJin Yamaguchi
Dec 17, 2020·Journal of Pediatric Orthopedics·Trevor J SheltonBrian M Haus
Aug 5, 2021·Archives of Orthopaedic and Trauma Surgery·Hyun Chul ShonJai Hyung Park

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