Factors predisposing to bacterial invasion and infection

American Journal of Surgery
Michael HeinzelmannTina Lam

Abstract

Bacterial infections remain important causes of morbidity and mortality in surgical patients. Our understanding of the effects of bacteria on the host, and also the defense mechanisms available to the host, is improving all the time. Modern tools in biochemistry, immunology, and molecular biology have provided powerful methods to further our understanding of the complex interactions that contribute to our host defense response. This review reflects current thinking regarding the factors that contribute to bacterial infection and host defense response. This review was compiled after an extensive review of the current and historical literature, and highlights a number of areas involved in the pathogenesis of bacterial infection. Bacteria can have a wide-ranging and deleterious effect on the host. Many different therapeutic approaches have been attempted to modulate the host response and limit the deleterious effects of bacteria. As our understanding of the underlying processes improves, these therapies should improve accordingly.

References

May 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·L ChedidE Lederer
Oct 1, 1992·Journal of Neuroimmunology·F Russo-Marie
Feb 1, 1992·Current Opinion in Immunology·M M Frank
May 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·T O'Reilly, O Zak
Jul 23, 1992·The New England Journal of Medicine·UNKNOWN Intravenous Immunoglobulin Collaborative Study GroupMichel-Pierre Glauser
Apr 1, 1992·International Journal of Immunopharmacology·I Azuma
Jun 11, 1991·American Journal of Surgery·W G CheadleH C Polk
Sep 1, 1991·Baillière's Clinical Gastroenterology·E J Adam, J E Page
Sep 11, 1991·Baillière's Clinical Gastroenterology·R N Gallinaro, H C Polk
May 26, 1990·Lancet·A R ExleyS Stephens
Apr 1, 1991·Archives of Surgery·J L Meakins
Feb 1, 1990·The British Journal of Surgery·M J HershmanH C Polk
Mar 1, 1989·The Journal of Antimicrobial Chemotherapy·T M Bergamini, H C Polk
Feb 1, 1972·The Journal of Surgical Research·H H Stone, T R Hester
Apr 1, 1973·The American Journal of Medicine·R J AndersonT C Eickhoff
Sep 1, 1984·Annals of Surgery·C W NohrJ L Meakins
Sep 1, 1983·The Journal of Trauma·E FaistG Heberer
Nov 11, 1982·The New England Journal of Medicine·E J ZieglerA I Braude
Sep 1, 1981·The British Journal of Surgery·R A Pettigrew
Mar 1, 1981·The American Journal of Medicine·T K Hunt
Dec 1, 1994·Diabetic Medicine : a Journal of the British Diabetic Association·P Pozzilli, R D Leslie
Aug 1, 1994·Current Opinion in Immunology·T Ganz, R I Lehrer
Aug 1, 1994·Current Opinion in Immunology·J E Galán
Apr 1, 1993·European Journal of Immunology·P R HutchingsI M Roitt
May 1, 1994·Annals of Internal Medicine·C NatansonR L Danner
Mar 1, 1993·Research in Immunology·B T Huber
Jan 14, 1993·The New England Journal of Medicine·C A Dinarello, S M Wolff
May 5, 1993·JAMA : the Journal of the American Medical Association·Z M QuezadoW D Hoffman
May 5, 1993·JAMA : the Journal of the American Medical Association·R C Bone

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Citations

Dec 20, 2003·American Journal of Surgery·Samir S Awad
Jul 9, 2005·Critical Care Medicine·Matthias TurinaHiram C Polk
Jun 27, 2007·Southern Medical Journal·Douglas Schlichting, Jill Shwed McCollam
Aug 28, 2009·Journal of Clinical Microbiology·Nadia BergeronSylvain Quessy
Jul 12, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Dariusz WaniczekEwa Nowakowska-Zajdel
Nov 4, 2008·Veterinary Immunology and Immunopathology·Mieke G R MatthijsLonneke Vervelde
Jul 10, 2004·Letters in Applied Microbiology·G M TantilloM Musti
Feb 16, 2012·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Akhil K SethKai P Leung
Jan 7, 2010·International Wound Journal·Rose A CooperKeith G Harding
Aug 3, 2005·American Journal of Infection Control·Thomas R Talbot
Jun 15, 2017·The Cochrane Database of Systematic Reviews·Jo C DumvilleJun Xia
Oct 23, 2018·Inflammatory Bowel Diseases·Nikolas DovrolisVassilis Valatas
Aug 8, 2009·Journal of Wound Care·R J White
Nov 13, 2010·British Journal of Nursing : BJN·Ann-Marie Aziz, Barbara Isalska
Feb 22, 2021·Drug Delivery and Translational Research·Pia KaiserMaike Windbergs
Oct 4, 2021·European Journal of Clinical Investigation·Fernanda GomesAnabela Salgueiro-Oliveira

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