Factors Related to Biological Sex Differences in Engagement with Healthcare Providers in Persons Living with HIV

AIDS and Behavior
Dawon BaikRebecca Schnall

Abstract

Little is known about how engagement with healthcare providers mediates the relationship between psychosocial factors (anxiety, depression, stigma) and medication adherence among persons living with HIV (PLWH). Moreover, little research has investigated potential biological sex differences in this relationship. We conducted a secondary analysis of data collected from four projects (N = 281) focused on improving health outcomes in PLWH. Males displayed (a) negative association between depression and engagement with healthcare providers (β = - 0.02, z = - 3.20, p = 0.001) and (b) positive association between engagement with healthcare providers and medication adherence (β = 0.55, OR = 1.73, z = 2.62, p = 0.009). Females showed no association between any of these factors. Anxiety and stigma were not significantly associated with medication adherence. Path analysis modeling for males had a very good fit (CFI = 1, TLI = 1, RMSEA = 0); none of the regression coefficients was significant for females. The significant relationship between depression and medication adherence among males was fully mediated by engagement with healthcare providers. Findings suggest that adherence interventions for PLWH should be tailored by biological sex.

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Dec 18, 2001·Research in Nursing & Health·B E BergerF R Lashley
Apr 24, 2003·Journal of General Internal Medicine·Barbara J TurnerWalter W Hauck
Sep 23, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·T Türmen
Jun 20, 2006·BMC Public Health·Aurea Redondo-SendinoFernando Rodríguez-Artalejo
Dec 23, 2006·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Kathryn WrightMaureen Frey
Aug 12, 2009·AIDS Patient Care and STDs·Nancy L SohlerChinazo O Cunningham
Jul 10, 2012·The Journal of the Association of Nurses in AIDS Care : JANAC·Ling HuangHonghong Wang
Oct 25, 2013·Lancet·Steven G DeeksDiane V Havlir
Nov 12, 2013·Journal of Women's Health·Marie ManteuffelAmy Steinkellner
Jun 25, 2015·Journal of Psychiatry & Neuroscience : JPN·Paul R Albert
Mar 20, 2016·British Journal of Anaesthesia·S HeschlM Rigaud
Jan 5, 2017·AIDS Patient Care and STDs·Rebecca SchnallSusan Olender
Mar 6, 2018·Current HIV/AIDS Reports·Eileen P Scully
Mar 7, 2018·Menopause : the Journal of the North American Menopause Society·Rebecca SchnallNancy Reame
Mar 27, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Maria ReiniusLars E Eriksson
Jan 10, 2019·International Journal of Medical Informatics·Melissa BeaucheminRebecca Schnall
Oct 1, 2019·Menopause : the Journal of the North American Menopause Society·Rebecca SchnallNancy Reame

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.