PMID: 9551684Apr 29, 1998Paper

Factors related to early mortality after transjugular intrahepatic portosystemic shunt for failed endoscopic therapy in acute variceal bleeding

Journal of Hepatology
D PatchA K Burroughs

Abstract

Uncontrolled variceal haemorrhage is the main indication for transjugular intrahepatic portosystemic shunt. However, mortality is 50% for this high-risk group. We have evaluated clinical and laboratory variables prior to transjugular intrahepatic portosystemic shunt in order to establish predictors of mortality, validated prospectively. Over a 4-year period, 367 patients were admitted with variceal bleeding. In 54 patients endoscopic therapy for acute variceal bleeding failed and they had emergency transjugular intrahepatic portosystemic shunt. Failure of therapy was defined as continued bleeding after 2 endoscopy sessions (n=39) or vasoconstrictor-resistant bleeding from gastric/ectopic varices (n=15). Thirty-three variables were analysed from data available immediately prior to transjugular intrahepatic portosystemic shunt. Twenty-six patients died within 6 weeks. In a multivariate analysis, 6 factors had independent prognostic value: moderate/severe ascites, requirement for ventilation, white cell blood count (WBC), platelet count (PLT), partial thromboplastin time with kaolin (PTTK) and creatinine. A prognostic index (PI) score was derived, in which presence of moderate/severe ascites, or need for ventilation, scored 1: PI=...Continue Reading

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Citations

May 12, 2005·Cardiovascular and Interventional Radiology·Aaron MontgomeryDarren W Postoak
May 5, 2004·Best Practice & Research. Clinical Gastroenterology·Martin Rössle, Daniel Grandt
May 23, 2003·Gastroenterology·Thomas D Boyer
Oct 26, 2002·Journal of Hepatology·M VangeliA K Burroughs
Feb 20, 2003·Journal of Hepatology·Jaime BoschRoberto Groszmann
Jul 25, 2000·Alimentary Pharmacology & Therapeutics·J VlachogiannakosA K Burroughs
Mar 25, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M MalinchocP C ter Borg
Mar 23, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Mark W RussoRobert S Brown
Dec 1, 2005·Seminars in Interventional Radiology·Jorge E Lopera
Jun 1, 2006·Seminars in Interventional Radiology·Renato RipamontiNilesh H Patel
Nov 13, 2004·Postgraduate Medical Journal·D N SamonakisA K Burroughs
May 28, 2005·Digestive Diseases·Andreas Ochs
Aug 14, 2012·International Journal of Hepatology·Gilles Pomier-LayrarguesPierre Perreault
Jul 3, 2009·Journal of Gastroenterology·Ulrich ThalheimerAndrew K Burroughs
Oct 14, 2011·International Journal of Hepatology·Sundeep J Punamiya, Deepak N Amarapurkar
Apr 9, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jaime BoschUNKNOWN International Study Group on rFVIIa in UGI Hemorrhage
Aug 4, 2006·Gastroentérologie Clinique Et Biologique·Jean-Pierre Vinel
Nov 13, 2002·Journal of Vascular and Interventional Radiology : JVIR·Hector FerralC Alex McMahan
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Feb 7, 2008·Liver International : Official Journal of the International Association for the Study of the Liver·John J KimRobert J Fontana
Oct 7, 2004·Journal of Hepatology·Marcello VangeliAndrew Kenneth Burroughs
Nov 28, 2015·Gastroenterología y hepatología·Esteban Ruiz-BlardJuan Carlos García-Pagán
Oct 7, 2005·Clinics in Liver Disease·Juan G AbraldesJaime Bosch
May 15, 2013·Revista de gastroenterología de México·R M Narváez-RiveraF J Bosques-Padilla
Feb 29, 2008·Journal of Hepatology·Jaime BoschJuan G Abraldes
Jun 30, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Jennifer GuyScott W Biggins
Feb 7, 2002·Journal of Vascular and Interventional Radiology : JVIR·Dheeraj K RajanTimothy W I Clark
Oct 7, 2005·Clinics in Liver Disease·Bimaljit Singh Sandhu, Arun J Sanyal
Jul 16, 2008·Gastroenterology·Juan Carlos Garcia-PagánUNKNOWN Budd-Chiari Syndrome-Transjugular Intrahepatic Portosystemic Shunt Group
May 8, 2001·European Journal of Gastroenterology & Hepatology·T BizollonC Trepo
Apr 21, 2004·European Journal of Gastroenterology & Hepatology·Ziad Hassoun, Gilles Pomier-Layrargues
Sep 24, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Alberto MonescilloElena Peña
Sep 18, 2007·European Journal of Gastroenterology & Hepatology·Erwin BieckerMichael Schepke
Dec 13, 2007·Journal of Clinical Gastroenterology·Juan G Abraldes, Jaime Bosch
Oct 11, 2005·European Journal of Gastroenterology & Hepatology·Ramasamy SaravananMartin G Lombard
Jul 1, 2009·Scandinavian Journal of Gastroenterology·Einar BjörnssonFlemming Bendtsen
May 7, 2019·Canadian Journal of Gastroenterology & Hepatology·Charlotte BouzbibMarika Rudler

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