Factors related to lymph node metastasis and the feasibility of endoscopic mucosal resection for treating poorly differentiated adenocarcinoma of the stomach

Endoscopy
Y D ParkY O Kweon

Abstract

Endoscopic mucosal resection (EMR) is currently not accepted as an alternative treatment to surgery in early gastric cancer (EGC) of the undifferentiated histologic type. The present retrospective analysis examined the correlation of various histologic factors with the presence of lymph node metastasis (LNM). A retrospective analysis on 234 patients with poorly differentiated EGC who underwent radical gastrectomy with D2 lymph node dissection was undertaken. Several clinicopathologic factors were investigated to identify predictive factors for LNM: age, sex, type of operation, tumor location, tumor size, gross type, ulceration, lymphatic invasion, and depth of invasion. Of the 234 lesions with poorly differentiated EGC, half (n = 116) already showed submucosal invasion in the resection specimen; 25.9 % of those (30/116) were limited to the upper third (SM1). Of the lesions confined to the mucosa, LNM was found in 3.4 % (4/118). With minor submucosal infiltration (SM1), the LNM rate was lower (0/30) in our patient population. Only with SM2/3 infiltration did the LNM rate sharply rise to around 30 %. The cut-off for submucosal infiltration depth was 500 microm (0/32 LNM), above which LNM rates were substantial (31.2 %; 24/77). Th...Continue Reading

Citations

Apr 17, 2013·Surgical Endoscopy·Da Hyun JungSung Hoon Noh
Nov 6, 2009·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Toshiaki HirasawaToshiharu Yamaguchi
Nov 6, 2009·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Seigo Kitano
Dec 4, 2010·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Junichirou NasuRieko Nishimura
Jul 26, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Yoji SanomuraKazuaki Chayama
Aug 6, 2013·Journal of Gastrointestinal Cancer·Fabrice CaillolMarc Giovannini
Oct 8, 2009·Annals of Surgery·Arnulf H HölscherElfriede Bollschweiler
Nov 5, 2010·World Journal of Gastroenterology : WJG·Chang-Mu SungCheng-Tang Chiu
Jun 17, 2011·World Journal of Gastroenterology : WJG·Hoon Jai ChunSang Young Seol
Jun 17, 2011·World Journal of Gastroenterology : WJG·Hang Lak LeeDae Young Cheung
Jun 17, 2011·World Journal of Gastroenterology : WJG·Kwang Bum ChoJae J Kim
May 30, 2013·World Journal of Gastroenterology : WJG·Tomoyuki OdagakiYutaka Saito
Dec 24, 2011·Gut and Liver·Ki Joo KangJae J Kim
Apr 20, 2014·World Journal of Gastroenterology : WJG·Choong Nam Shim, Sang Kil Lee
May 2, 2014·World Journal of Gastroenterology : WJG·Yang Won MinJae J Kim
Apr 1, 2014·Gastrointestinal Endoscopy Clinics of North America·Mi-Young KimJoo Young Cho
Apr 2, 2015·Surgical Endoscopy·Savio G Barreto, John A Windsor
May 30, 2009·Journal of the American College of Surgeons·Kozo YoshikawaToshiharu Yamaguchi
Mar 31, 2009·Gastrointestinal Endoscopy·Jie-Hyun KimJae Bock Chung
May 8, 2010·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yorimasa YamamotoMasahiro Igarashi
Mar 7, 2015·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Yusuke HoriuchiHiroshi Takahashi
Apr 15, 2016·Langenbeck's Archives of Surgery·Thomas HaistDietmar Lorenz
May 30, 2012·International Journal of Surgery·Baldwin Po Man Yeung, Terence Gourlay
Apr 30, 2013·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Moon Han ChoiMoon Sung Lee
Feb 25, 2014·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Min Woo ChungSung Bum Cho
Nov 15, 2011·Journal of Gastric Cancer·Ji Yeong AnSung Hoon Noh
Oct 18, 2016·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Toshiyasu OjimaHiroki Yamaue
Jan 26, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Xudong ZhaoHua Li
Nov 14, 2017·Journal of Gastroenterology and Hepatology·Yang Won MinDong Hyun Sinn

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