Factors related to previous tuberculosis treatment of patients with multidrug-resistant tuberculosis in Bangladesh

BMJ Open
Mahfuza RifatAbul Hasnat Milton

Abstract

Previous tuberculosis (TB) treatment status is an established risk factor for multidrug-resistant TB (MDR-TB). This study explores which factors related to previous TB treatment may lead to the development of multidrug resistant in Bangladesh. We previously conducted a large case-control study to identify risk factors for developing MDR-TB in Bangladesh. Patients who had a history of previous TB treatment, either MDR-TB or non-MDR-TB, were interviewed about their previous treatment episode. This study restricts analysis to the strata of patients who have been previously treated for TB. Information was collected through face-to-face interviews and record reviews. Unadjusted and multivariable logistic regression was used for data analysis. Central-level, district-level and subdistrict-level hospitals in rural and urban Bangladesh. The strata of previously treated patients include a total of 293 patients (245 current MDR-TB; 48 non-MDR-TB). Overall, 54% of patients received previous TB treatment more than once, and all of these patients were multidrug resistant. Patients with MDR-TB were more likely to have experienced the following factors: incomplete treatment (OR 4.3; 95% CI 1.7 to 10.6), adverse reactions due to TB treatment (...Continue Reading

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Citations

Oct 14, 2017·Health Policy and Planning·Mishal S KhanSithu Aung
Jan 15, 2020·The American Journal of Tropical Medicine and Hygiene·Sakarn CharoensakulchaiPhunlerd Piyaraj
Apr 24, 2019·Epidemiology and Health·Adel Hussein EldumaKourosh Holakouie-Naieni
Jan 13, 2021·BMC Infectious Diseases·Zeeba Zahra SultanaAhmed Hossain

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BETA
PCR
biopsy

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Stata

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